Ixabiso elihlawulelwayo I-viscosity ephezulu ye-hydroxyethyl cellulose HEC yokusetyenziswa kweoli
Bhela "uMthengi kuqala, Ogqwesileyo kuqala" engqondweni, sisebenza ngokusondeleyo nabathengi bethu kwaye sibabonelele ngeenkonzo ezisebenzayo kunye neengcali ngexabiso elihlawulelwayo I-viscosity ephezulu ye-hydroxyethyl cellulose HEC yokusetyenziswa kwe-oyile, Ishishini lethu lamkele ngokufudumeleyo abahlobo abasondeleyo abavela kuyo yonke indawo kwindawo oya kuyo. ukuya, ukuhlola kunye uthethathethwano umbutho.
Yiba “uMthengi kuqala, Ogqwesileyo kuqala” engqondweni, sisebenza ngokusondeleyo nabathengi bethu kwaye sibabonelele ngeenkonzo ezisebenzayo nezikhethekileyoChina HEC kunye neHydroxyethyl CelluloseUkuza kuthi ga ngoku, umba wethu onxulunyaniswa nomshicileli we-dtg a4 unokuboniswa kuninzi lwezizwe zangaphandle kunye namaziko asezidolophini, afunwayo ngokulula yitrafikhi ekujoliswe kuyo. Sonke sicinga ukuba ngoku sinamandla apheleleyo okukubonisa ngezinto ezithengiswayo ezanelisekileyo. Unqwenela ukuqokelela izicelo zezinto zakho kwaye uvelise intsebenziswano yexesha elide yentsebenziswano. Siyathembisa ngokunzulu:Umgangatho ophezulu weCsame, ixabiso elingcono; ixabiso lokuthengisa ngqo, umgangatho ophezulu.
Ingcaciso yeMveliso
IHydroxypropyl Methyl Cellulose(HPMC)
Ifomula yeemolekyuli
IHypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokutshintsha 2910, 2906, 2208 (USP)
Iipropati Zomzimba
- Umgubo omhlophe okanye otyheli omhlophe
-Inyibilika kwisinyibilikisi esixutyiweyo okanye esinamanzi
- Ukwenza ifilimu ecacileyo xa ususa i-solvent
- Akukho ukuphendula kweekhemikhali kunye neziyobisi ngenxa yepropati yayo engeyiyo ionic
- Ubunzima beMolekyuli : 10,000 ~ 1,000,000
- Inqaku leGel: 40 ~ 90℃
Indawo yokutshisa ngokuzenzekelayo: 360℃
IHydroxypropyl Methylcellulose (HPMC) iBanga loShishino yi-Hypromellose excipient yeyeza kunye neyongezelelo, enokusetyenziswa njenge-thickener, dispersant, emulsifier kunye ne-agent-forming agent.
I-QualiCell Cellulose ether iqulethe i-methyl cellulose (USP, EP, BP, CP) kunye neentlobo ezintathu endaweni ye-hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) nganye ifumaneka kumabakala amaninzi ahlukeneyo kwimveliso ye-viscosity.HPMC ithathwe kwimveliso yendalo esulungekileyo i-cotton linter kunye ne-pulp yomthi, ukuhlangabezana nazo zonke iimfuno ze-USP, i-EP, i-BP, kunye ne-Kosher kunye Iziqinisekiso zeHalal.
Kwinkqubo yokuvelisa, ikotoni yendalo ehlanjululwe kakhulu i-etherified nge-methyl chloride okanye kunye nokudibanisa i-methyl chloride kunye ne-propylene oxide ukwenza i-ether e-soluble yamanzi, i-non-ionic cellulose ether. Akukho zixhobo zezilwanyana ezisetyenziselwa ukuveliswa kwe-HPMC.HPMC zingasetyenziswa njenge-binder kwiifom zedosi eqinileyo ezifana neepilisi kunye neegranules. Ikwasebenza nemisebenzi eyahlukeneyo, imizekelo, ekuphuculeni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid ekhuselayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, kunye nokubunjwa kwefilimu.
I-QualiCell HPMC inikezela ngemisebenzi eyahlukeneyo efana nokugcinwa kwamanzi, i-colloid yokukhusela, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Yikhompawundi engeyo-ionic exhathisayo kwityuwa ngaphandle kwaye izinzile kuluhlu olubanzi lwe-pH. Usetyenziso oluqhelekileyo lwe-HPMC zizibophelelo kwiifomu zedosi eqinileyo ezifana neepilisi kunye neegranuli okanye isingqimba sokwenziwa kolwelo.
I-Pharma HPMC iza kwiindidi ze-viscosity ezahlukeneyo ukusuka kwi-3 ukuya kwi-200,000 cps, kwaye ingasetyenziselwa ngokubanzi ukugquma ithebhulethi, i-granulation, i-binder, i-thickener, i-stabilizer kunye nokwenza i-capsule ye-HPMC yemifuno.
Ukucaciswa kwemichiza
| I-Hypromelose Inkcazo | 60E ( 2910 ) | 65F ( 2906 ) | 75K ( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
IBanga leMveliso
| I-Hypromelose Inkcazo | 60E ( 2910 ) | 65F ( 2906 ) | 75K ( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Isicelo
I-Pharma Grade HPMC yenza ukuba kuveliswe iifomyula ezilawulwayo-ezikhutshwayo ngokulula kweyona ndlela isetyenziswa kakhulu kwi-tablet-binding mechanism. IBanga le-Pharma libonelela ngokuhamba kakuhle komgubo, ukufana komxholo, kunye nokunyanzeliswa, kubenza bafanelekele ukunyanzeliswa ngokuthe ngqo.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| Unyibiliko lweLaxative | 75K4000,75K100000 | 3-30% |
| Iikhremu, iiGel | 60E4000,75K4000 | 1-5% |
| Ukulungiswa kwamehlo | 60E4000 | 01.-0.5% |
| Amalungiselelo amathontsi eliso | 60E4000 | 0.1-0.5% |
| I-arhente yokunqumamisa | 60E4000, 75K4000 | 1-2% |
| Ii-antacids | 60E4000, 75K4000 | 1-2% |
| Iitafile zeBinder | 60E5, 60E15 | 0.5-5% |
| Indibano eManzi iGranulation | 60E5, 60E15 | 2-6% |
| Iingubo zeCwecwe | 60E5, 60E15 | 0.5-5% |
| Ukukhutshwa okuLawulwayo kweMatrix | 75K100000,75K15000 | 20-55% |
Iimpawu kunye neeNzuzo
- Ukuphucula iimpawu zokuhamba kwemveliso
- Yehlisa amaxesha okusebenza
- Iiprofayili ezifanayo, ezizinzileyo zokupheliswa
- Ukuphucula ukufana komxholo
- Ukunciphisa iindleko zemveliso
- Igcina amandla okuqina emva kokudityaniswa kabini (i-roller compaction) inkqubo
Ukupakishwa
Ukupakishwa okusemgangathweni yi-25kg / igubu
I-20'FCL: iitoni ezili-9 ezine-palletized; Iitoni ezili-10 ezingafakwanga iipaleti.
I-40'FCL: i-18 toni ene-palletized; Iitoni ezingama-20 ezingafakwanga iipaleti.
Bhela "uMthengi kuqala, Ogqwesileyo kuqala" engqondweni, sisebenza ngokusondeleyo nabathengi bethu kwaye sibabonelele ngeenkonzo ezisebenzayo kunye neengcali ngexabiso elihlawulelwayo I-viscosity ephezulu ye-hydroxyethyl cellulose HEC yokusetyenziswa kwe-oyile, Ishishini lethu lamkele ngokufudumeleyo abahlobo abasondeleyo abavela kuyo yonke indawo kwindawo oya kuyo. ukuya, ukuhlola kunye uthethathethwano umbutho.
Ixabiso elihlawulelwayo I-China HEC kunye ne-Hydroxyethyl cellulose, Ukuza kuthi ga ngoku, into yethu eyayanyaniswa nomshicileli we-dtg a4 inokuboniswa kuninzi lwezizwe zangaphandle kunye nakumaziko asezidolophini, afunwayo ngokulula yitrafikhi ekujoliswe kuyo. Sonke sicinga ukuba ngoku sinamandla apheleleyo okukubonisa ngezinto ezithengiswayo ezanelisekileyo. Unqwenela ukuqokelela izicelo zezinto zakho kwaye uvelise intsebenziswano yexesha elide yentsebenziswano. Siyathembisa ngokunzulu:Umgangatho ophezulu weCsame, ixabiso elingcono; ixabiso lokuthengisa ngqo, umgangatho ophezulu.
