Umgangatho oPhakamileyo we-HPMC kwiBanga le-Pharma kuLwakhiwo lwezoKhemesti
Usukelo lwethu kufuneka lube kukudibanisa kunye nokuphucula umgangatho ophezulu kunye nenkonzo yempahla yangoku, okwangoku sihlala sisenza iimveliso ezintsha ukwanelisa iifowuni ezahlukeneyo zabathengi zoMgangatho oPhezulu we-HPMC kwiBanga le-Pharma loLwakhiwo lwe-Pharmaceutical, Okwangoku, igama lequmrhu linokuninzi. ngaphezu kwama-4000 eentlobo zeemveliso kwaye yafumana iwonga elihle kakhulu kunye nezabelo ezinkulu kwimarike yangoku yasekhaya nakwamanye amazwe.
Injongo yethu kufuneka ibe kukudibanisa kunye nokuphucula umgangatho ophezulu kunye nenkonzo yempahla yangoku, okwangoku sihlala sisenza iimveliso ezintsha ukwanelisa iifowuni ezahlukeneyo zabathengiI-HPMC yaseTshayina kunye ne-Adhesive, Sidibanisa uyilo, ukuvelisa kunye nokuthumela ngaphandle kunye nabasebenzi abanobuchule abangaphezu kwe-100, inkqubo engqongqo yokulawula umgangatho kunye namava etekhnoloji.Sigcina ubudlelwane beshishini bexesha elide kunye nomthengisi kunye nabanikezeli benza amazwe angaphezu kwama-50, njenge-USA, UK, Canada, Europe kunye Afrika njl.
Ingcaciso yeMveliso
IHydroxypropyl Methyl Cellulose(HPMC)
Ifomula yeemolekyuli
IHypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokutshintsha 2910, 2906, 2208 (USP)
Iipropati Zomzimba
- Umgubo omhlophe okanye otyheli omhlophe
-Inyibilika kwisinyibilikisi esixutyiweyo okanye esinamanzi
- Ukwenza ifilimu ecacileyo xa ususa i-solvent
- Akukho ukuphendula kweekhemikhali kunye neziyobisi ngenxa yepropati yayo engeyiyo ionic
- Ubunzima beMolekyuli : 10,000 ~ 1,000,000
- Inqaku leGel: 40 ~ 90℃
Indawo yokutshisa ngokuzenzekelayo: 360℃
IHydroxypropyl Methylcellulose (HPMC) iBanga loShishino yi-Hypromellose excipient yeyeza kunye neyongezelelo, enokusetyenziswa njenge-thickener, dispersant, emulsifier kunye ne-agent-forming agent.
I-QualiCell Cellulose ether iqulethe i-methyl cellulose (USP, EP, BP, CP) kunye neentlobo ezintathu endaweni ye-hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) nganye ifumaneka kumabakala amaninzi ahlukeneyo kwimveliso ye-viscosity.HPMC ithathwe kwimveliso yendalo esulungekileyo i-cotton linter kunye ne-pulp yomthi, ukuhlangabezana nazo zonke iimfuno ze-USP, i-EP, i-BP, kunye ne-Kosher kunye Iziqinisekiso zeHalal.
Kwinkqubo yokuvelisa, ikotoni yendalo ehlanjululwe kakhulu i-etherified nge-methyl chloride okanye kunye nokudibanisa i-methyl chloride kunye ne-propylene oxide ukwenza i-ether e-soluble yamanzi, i-non-ionic cellulose ether. Akukho zixhobo zezilwanyana ezisetyenziselwa ukuveliswa kwe-HPMC.HPMC zingasetyenziswa njenge-binder kwiifom zedosi eqinileyo ezifana neepilisi kunye neegranules. Ikwasebenza nemisebenzi eyahlukeneyo, imizekelo, ekuphuculeni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid ekhuselayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, kunye nokubunjwa kwefilimu.
I-QualiCell HPMC inikezela ngemisebenzi eyahlukeneyo efana nokugcinwa kwamanzi, i-colloid yokukhusela, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Yikhompawundi engeyo-ionic exhathisayo kwityuwa ngaphandle kwaye izinzile kuluhlu olubanzi lwe-pH. Usetyenziso oluqhelekileyo lwe-HPMC zizibophelelo kwiifomu zedosi eqinileyo ezifana neepilisi kunye neegranuli okanye isingqimba sokwenziwa kolwelo.
I-Pharma HPMC iza kwiindidi ze-viscosity ezahlukeneyo ukusuka kwi-3 ukuya kwi-200,000 cps, kwaye ingasetyenziselwa ngokubanzi ukugquma ithebhulethi, i-granulation, i-binder, i-thickener, i-stabilizer kunye nokwenza i-capsule ye-HPMC yemifuno.
Ukucaciswa kwemichiza
| I-Hypromelose Inkcazo | 60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
IBanga leMveliso
| I-Hypromelose Inkcazo | 60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Isicelo
I-Pharma Grade HPMC yenza ukuba kuveliswe iifomyula ezilawulwayo-ezikhutshwayo ngokulula kweyona ndlela isetyenziswa kakhulu kwi-tablet-binding mechanism. IBanga le-Pharma libonelela ngokuhamba kakuhle komgubo, ukufana komxholo, kunye nokunyanzeliswa, kubenza bafanelekele ukunyanzeliswa ngokuthe ngqo.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| Unyibiliko lweLaxative | 75K4000,75K100000 | 3-30% |
| Iikhremu, iiGel | 60E4000,75K4000 | 1-5% |
| Ukulungiswa kwamehlo | 60E4000 | 01.-0.5% |
| Amalungiselelo amathontsi eliso | 60E4000 | 0.1-0.5% |
| I-arhente yokunqumamisa | 60E4000, 75K4000 | 1-2% |
| Ii-antacids | 60E4000, 75K4000 | 1-2% |
| Iitafile zeBinder | 60E5, 60E15 | 0.5-5% |
| Indibano eManzi iGranulation | 60E5, 60E15 | 2-6% |
| Iingubo zeCwecwe | 60E5, 60E15 | 0.5-5% |
| Ukukhutshwa okuLawulwayo kweMatrix | 75K100000,75K15000 | 20-55% |
Iimpawu kunye neeNzuzo
- Ukuphucula iimpawu zokuhamba kwemveliso
- Yehlisa amaxesha okusebenza
- Iiprofayili ezifanayo, ezizinzileyo zokupheliswa
- Ukuphucula ukufana komxholo
- Ukunciphisa iindleko zemveliso
- Igcina amandla okuqina emva kokudityaniswa kabini (i-roller compaction) inkqubo
Ukupakishwa
Ukupakishwa okusemgangathweni yi-25kg / igubu
I-20'FCL: iitoni ezili-9 ezine-palletized; Iitoni ezili-10 ezingafakwanga iipaleti.
I-40'FCL: i-18 toni ene-palletized; Iitoni ezingama-20 ezingafakwanga iipalletti. Injongo yethu kufuneka ibe kukuhlanganisa kunye nokuphucula umgangatho ophezulu kunye nenkonzo yempahla yangoku, okwangoku sihlala siyila iimveliso ezintsha ukwanelisa iminxeba yabathengi abahlukeneyo kuMgangatho oPhezulu we-HPMC kwiBanga le-Pharma loLwakhiwo lwezamayeza, Okwangoku, Igama lombutho lineentlobo ezininzi zeemveliso ezingaphezulu kwama-4000 kwaye lifumene iwonga elihle kakhulu kunye nezabelo ezinkulu kwimakethi yangoku yangaphakathi nangaphandle.
Umgangatho ophezulu weI-HPMC yaseTshayina kunye ne-Adhesive, Sidibanisa uyilo, ukuvelisa kunye nokuthumela ngaphandle kunye nabasebenzi abanobuchule abangaphezu kwe-100, inkqubo engqongqo yokulawula umgangatho kunye namava etekhnoloji.Sigcina ubudlelwane beshishini bexesha elide kunye nomthengisi kunye nabanikezeli benza amazwe angaphezu kwama-50, njenge-USA, UK, Canada, Europe kunye Afrika njl.
