Izinto eziluncedo kunye neentlobo ze-HPMC

I-Hydroxypropylmethylcellulose (HPMC) yikhompawundi esetyenziswa ngokubanzi kunye noluhlu olubanzi lwezicelo zoshishino, zorhwebo, kunye nezempilo. I-HPMC yikhompawundi engenavumba, ayinancasa, kwaye ayinatyhefu ephuma kwiselulosi. Yikhompawundi enyibilikayo emanzini esetyenziswa kwiintlobo ngeentlobo zokutya, izithambiso, iziyobisi, kunye namayeza. I-HPMC yaziwa ngobuchule bayo bokwenza ifilim, iipropati zokuncamathelisa kunye nomthamo wokugcina amanzi. Ikwaziwa ngokuba yi-viscosity egqwesileyo, uzinzo kunye nokuhambelana nezinto ezahlukeneyo.

Iindidi ze-HPMC:

Kukho iintlobo ezininzi ze-HPMC kwimarike, nganye ineempawu ezizodwa kunye neekhemikhali. Nazi ezinye iintlobo eziqhelekileyo ze-HPMC:

1. I-HPMC ye-viscosity ephantsi:

I-viscosity ephantsi ye-HPMC ibonakala ngobunzima obuphantsi bemolekyuli kunye neqondo eliphantsi lokuthatha indawo. Ngenxa yeempawu zayo zokubopha ezigqwesileyo, isetyenziswa ngokuqhelekileyo njenge-binder kunye ne-disintegrant kwiipilisi.

2. Medium viscosity HPMC:

Medium viscosity HPMC has a medium molecular weight and degree of substitution. Ngokuqhelekileyo isetyenziselwa ukuzinzisa i-emulsions, ukumiswa kunye ne-foam kwishishini lokutya kunye nesiselo.

3. High viscosity HPMC:

Viscosity High HPMC luphawulwa ubunzima molekyuli eliphezulu kunye neqondo eliphezulu lokuthatha indawo. Isetyenziswa ngokuqhelekileyo njenge-thickener kunye ne-gelling agent kumashishini okutya kunye ne-cosmetic.

4. Unyango lwe-HPMC:

I-HPMC enyangwayo ngomphezulu iphathwa ngeekhemikhali ezahlukeneyo ukuguqula iimpawu zayo zomphezulu. Ngokuqhelekileyo isetyenziswe njengesongezo kwishishini lokwakha ukuphucula iipropati zezinto ezisekelwe kwi-samente.

Izinto eziluncedo zeHPMC:

I-HPMC izisa iinzuzo ezininzi kumashishini ahlukeneyo. Nazi ezinye iingenelo ezinokubakho ze-HPMC:

1. Ikhuselekile kwaye ayinayo ityhefu:

Enye yeenzuzo eziphambili ze-HPMC kukhuseleko kunye nokungabi yingozi. I-HPMC ithathwe kwi-cellulose, ikhompawundi yendalo. Kwakhona ayikuthukuthezi ulusu, amehlo kunye ne-mucous membranes, iyenza ibe yinto ekhuselekileyo kwiimveliso ezahlukeneyo.

2. Ukunyibilika kwamanzi:

I-HPMC inyibilika kakhulu emanzini, iyenza ibe sisithako esihle kakhulu kwiimveliso ezahlukeneyo ezifuna ukugcinwa kwamanzi kunye nokuncamathela. Ngokuqhelekileyo isetyenziswa njenge-binder kunye ne-disintegrant kumashishini okutya kunye namayeza.

3. Isakhono sokwenza ifilimu:

I-HPMC inobuchule obugqwesileyo bokwenza ifilim, iyenza ibe sisithako esigqwesileyo kwiimveliso ezahlukeneyo ezifuna iingubo zokukhusela. Isetyenziswa ngokuqhelekileyo kwishishini lamachiza kwi-coating tablets kunye ne-capsules.

4. Viscosity kunye neempawu zokujiya:

I-HPMC ine-viscosity egqwesileyo kunye neempawu ezityebisayo, iyenza ibe sisithako esibalaseleyo kwiimveliso ezahlukeneyo ezifuna ukutyeba, ukuthungwa okugudileyo. Iqhele ukusetyenziswa kumashishini okutya kunye nezithambiso ukujiya iisosi kunye neloshini.

5. Uzinzo kunye nokuhambelana:

I-HPMC inozinzo olubalaseleyo kunye nokuhambelana nezinto ezahlukeneyo, iyenza ibe sisithako esibalaseleyo kwiimveliso ezahlukeneyo ezifuna uzinzo kunye nokuhambelana. Ngokuqhelekileyo isetyenziswa kwishishini loxubo mayeza ukuzinzisa ukwakheka kwamachiza.

I-HPMC yikhompawundi enemisebenzi emininzi ezisa iinzuzo ezininzi kumashishini ahlukeneyo aquka ukutya, izinto zokuthambisa kunye namayeza. Iimpawu zayo ezikhethekileyo zomzimba kunye neekhemikhali zenza ukuba ibe yinto ebalaseleyo kwiimveliso ezahlukeneyo, kubandakanywa izibophelelo, i-disintegrants, i-emulsions, i-suspending agents, i-foams, i-thickeners, i-gelling agents, kunye nabenzi befilimu. HPMC kwakhona ikhuselekile kwaye non-ityhefu, iyenza isithako ebalaseleyo kwiintlobo ngeentlobo zeemveliso ezifuna ukhuseleko kunye non-ityhefu. Iindidi ezahlukeneyo ze-HPMC ezikhoyo kwimarike zibonelela ngamashishini ahlukeneyo ngeendlela ezahlukeneyo zokukhetha kuzo ngokweemfuno zabo kunye neemfuno.