Ngaba i-hydroxypropyl methylcellulose kunye ne-hypromellose ziyafana?

I-Hydroxypropyl methylcellulose (HPMC) kunye ne-hypromellose ngokwenene ziyikhompawundi enye, kwaye amagama ahlala esetyenziswa ngokutshintshanayo. Lawa ngamagama anzima kwiintlobo eziqhelekileyo zeepolymers ezisekelwe kwi-cellulose ezinoluhlu olubanzi lwezicelo kumashishini ahlukeneyo kuquka amayeza, ukutya kunye nezithambiso.

1. Ubume beMichiza kunye nokwakheka:

I-Hydroxypropylmethylcellulose (HPMC) yinguqulelo eyenziweyo ye-cellulose, i-polymer yendalo efumaneka kwiindonga zeeseli zezityalo. Ubume bemichiza ye-HPMC ifunyenwe ngokuzisa i-hydroxypropyl kunye namaqela e-methyl ngokwesiseko seselulosi. Iqela le-hydroxypropyl lenza i-cellulose i-soluble ngakumbi emanzini, kwaye iqela le-methyl liphucula ukuzinza kwalo kwaye linciphisa ukusebenza kwalo kwakhona.

2. Inkqubo yokwenziwa kwemveliso:

Ukuveliswa kwe-hydroxypropyl methylcellulose kubandakanya ukunyanga i-cellulose nge-propylene oxide ukwazisa amaqela e-hydroxypropyl kunye ne-methyl chloride ukongeza amaqela e-methyl. I-degree of substitution (DS) ye-hydroxypropyl kunye ne-methyl inokulungelelaniswa ngexesha lenkqubo yokuvelisa, okukhokelela kumabakala ahlukeneyo e-HPMC eneempawu ezahlukeneyo.

3. Iimpawu ezibonakalayo:

I-HPMC imhlophe ukuya kumgubo omhlophe kancinci, ayinavumba kwaye ayinancasa. Iimpawu zayo ezibonakalayo, ezifana ne-viscosity kunye ne-solubility, zixhomekeke kwinqanaba lokutshintshwa kunye nobunzima be-molecular of polymer. Kwiimeko eziqhelekileyo, i-soluble ngokulula emanzini, yenza isisombululo esicacileyo nesingenambala.

4. Iinjongo zonyango:

Esinye sezicelo eziphambili ze-HPMC kushishino lwamayeza. Isetyenziswa ngokubanzi njenge-excipient yamachiza kwaye idlala iindima ezahlukeneyo kumalungiselelo amayeza. I-HPMC iqhele ukufunyanwa kwiifom zedosi yodosi yomlomo eqinileyo njengeepilisi, iipilisi, iipilisi. Isebenza njenge-binder, i-disintegrant, kunye ne-arhente yokukhululwa elawulwayo, igalelo kuzinzo jikelele kunye ne-bioavailability yechiza.

5. Indima kumalungiselelo okukhululwa alawulwayo:

Ukukwazi kwe-HPMC ukwenza iijeli kwizisombululo ezinamanzi kuyenza ixabiseke ekuqulunqweni kweziyobisi ezilawulwayo. Ngokutshintsha i-viscosity kunye ne-gel-forming properties, izazinzulu zamachiza zinokulawula izinga lokukhululwa kwezithako ezisebenzayo, ngaloo ndlela zifezekise isenzo seziyobisi eziqhubekayo kunye nexesha elide.

6. Ukusetyenziswa kushishino lokutya:

Kwishishini lokutya, i-HPMC isetyenziswa njenge-thickener, stabilizer kunye ne-emulsifier. Iphucula ukuthungwa kokutya okwahlukeneyo, kubandakanywa iisosi, iisuphu kunye neemveliso zobisi. Ukongeza, i-HPMC isetyenziselwa ukubhaka okungekho gluten-free ukunyusa isakhiwo kunye neempawu zokufuma kwiimveliso ezingenagluten.

7. Izinto zokwakha kunye nezinto zokwakha:

I-HPMC isetyenziswa kushishino lolwakhiwo kwiimveliso ezifana nokuncamathelisa iithayile, iiplasta ezisekwe kwisamente kunye nezinto ezisekwe kwigypsum. Iphucula ukusetyenzwa, ukugcinwa kwamanzi kunye neempawu zokubambelela kwezi mveliso.

8. Izinto zokuthambisa kunye neemveliso zokhathalelo lomntu:

I-Hypromellose ikwasisithako esiqhelekileyo kwizithambiso kunye neemveliso zokhathalelo lomntu. Isetyenziswa kwi-creams, lotions kunye ne-shampoos ngenxa yokuqina kwayo kunye nokuzinza kwayo. Ukongezelela, kunceda ukuphucula ukuthungwa ngokubanzi kunye nokuvakalelwa kwemveliso.

9. Ukugqunywa kwefilimu kumayeza:

I-HPMC isetyenziswa kakhulu kwishishini lamachiza ukugquma ifilim yamacwecwe. Iipilisi ezigqunywe ngefilimu zibonelela ngenkangeleko ephuculweyo, incasa yokufihla incasa kunye nokukhuselwa kwizinto ezisingqongileyo. Iifilimu ze-HPMC zibonelela ngengubo egudileyo nefanayo, iphucula umgangatho uwonke wemveliso yeziyobisi.

13. Isiphelo:

IHydroxypropyl methylcellulose (HPMC) kunye ne-hypromellose zibhekisa kwipolymer esekwe kwi-cellulose eneentlobo ngeentlobo zezicelo kumayeza, ukutya, izimonyo kunye nokwakhiwa. Iimpawu zayo ezizodwa, ezifana nokunyibilika, ukuzinza kunye nokubola kwe-biodegradability, igalelo ekusetyenzisweni kwayo ngokubanzi. Ukuguquguquka kweHPMC kumashishini ahlukeneyo kuqaqambisa ukubaluleka kwayo njengesixhobo esinemisebenzi emininzi, kwaye iyaqhubekauphendlo nophuhliso lunokuveza usetyenziso olongezelelweyo kwixesha elizayo.

Olu phononongo lubanzi lujolise ekuboneleleni ngeenkcukacha ezithe kratya ze-hydroxypropyl methylcellulose kunye ne-hypromellose, ukucacisa ukubaluleka kwazo kwiinkalo ezahlukeneyo, kunye nokucacisa indima yazo ekubumbeni iimveliso ezininzi kunye nokuqulunqwa.