IHydroxypropyl methylcellulose phantse ayinyibiliki kwi-ethanol epheleleyo kunye ne-acetone. Isisombululo esinamanzi sizinzile kakhulu kwiqondo lokushisa lokushisa kwaye siyakwazi i-gel kwiqondo lokushisa eliphezulu. Uninzi lwehydroxypropyl methylcellulose kwimarike ngoku yeyamanzi abandayo (amanzi obushushu begumbi, amanzi etephu) uhlobo lwangoko nangoko. Amanzi abandayo ngoko nangoko i-HPMC iya kuba lula kwaye ikhuseleke ngakumbi ukuyisebenzisa. I-HPMC kufuneka yongezwe ngokuthe ngqo kwisisombululo samanzi abandayo emva kwemizuzu elishumi ukuya kwamashumi alithoba ukujiya ngokuthe chu. Ukuba imodeli ekhethekileyo, kufuneka ixutywe ngamanzi ashushu ukuze ihlakazeke, ize igalelwe emanzini abandayo ukuze ichithe emva kokupholisa.
Xa iimveliso ze-HPMC zongezwa ngokuthe ngqo emanzini, ziya kubumba kwaye zinyibilike, kodwa oku kupheliswa kucotha kakhulu kwaye kunzima. Ezi ndlela zintathu zilandelayo zokuchithwa ziyacetyiswa, kwaye abasebenzisi banokukhetha eyona ndlela ifanelekileyo ngokwemeko yokusetyenziswa (ingakumbi kumanzi abandayo iHPMC ekhawulezileyo).
Indlela yokuchithwa kunye nezilumkiso ze-HPMC
1. Indlela yamanzi abandayo: Xa kufuneka yongezwe ngokuthe ngqo kwisisombululo esinamanzi esiqhelekileyo sobushushu, kungcono ukusebenzisa uhlobo lokusasazwa kwamanzi abandayo. Emva kokongeza i-viscosity, ukuhambelana kuya kwanda ngokuthe ngcembe kwimfuno yesalathisi.
2. Indlela yokuxuba i-powder: I-HPMC yomgubo kunye nomlinganiselo ofanayo okanye ngaphezulu kwamanye amacandelo e-powdery achithwa ngokupheleleyo ngokuxuba okomileyo, kwaye emva kokongeza amanzi ukuchithwa, i-HPMC inokuchithwa ngeli xesha kwaye ayiyi kuphinda idibanise. Enyanisweni, kungakhathaliseki ukuba luhlobo luni lwe-hydroxypropyl methylcellulose. Inokomisa idibaniswe ngokuthe ngqo kwezinye izinto.
3. Indlela yokumanzisa i-solvent ye-Organic: I-HPMC ihlakazwe kwangaphambili okanye imanziswe nge-solvents ye-organic, efana ne-ethanol, i-ethylene glycol okanye i-oyile, kwaye emva koko inyibilika emanzini, kwaye i-HPMC inokuchithwa kakuhle.
Ngexesha lenkqubo yokuchithwa, ukuba kukho i-agglomeration, iya kusongwa. Esi sisiphumo sokungalinganisi ukulinganisa, ngoko kuyimfuneko ukukhawuleza ukukhawuleza. Ukuba kukho amaqamza kwi-dissolution, kungenxa yomoya obangelwa kukuphazamiseka okungalinganiyo, kwaye isisombululo sivumelekile ukuba sime iiyure ezingama-2- 12 (ixesha elithile lixhomekeke ekungqinelani kwesisombululo) okanye ukucoca, ukunyanzeliswa kunye nezinye iindlela. ukususa, ukongeza isixa esifanelekileyo se-defoamer nako kunokuphelisa le meko. Ukongeza inani elifanelekileyo le-defoamer nako kunokuphelisa le meko.
Ekubeni i-hydroxypropyl methylcellulose isetyenziswa kumashishini ahlukeneyo, kubaluleke kakhulu ukuqonda indlela yokuchithwa kwe-hydroxypropyl methylcellulose ukuze isetyenziswe ngokuchanekileyo. Ukongezelela, abasebenzisi bayakhunjuzwa ukuba banikele ingqalelo ekukhuselweni kwelanga, ukukhuselwa kwemvula kunye nokukhuselwa komswakama ngexesha lokusetyenziswa, ukuphepha ukukhanya okuthe ngqo, kunye nokugcina kwindawo evaliweyo neyomileyo. Gwema ukudibana nemithombo yokutshisa kwaye ugweme ukubunjwa kothuli oluninzi kwiindawo ezivaliweyo ukukhusela iingozi zokuqhuma.
Ixesha lokuposa: Jun-20-2023