HPMC kwi Skim idyasi

IHydroxypropyl methyl cellulose (HPMC) viscosity yeSkim coat ?

– impendulo: Idyasi ye-Skim ilungile ngokuqhelekileyo i-HPMC 100000cps, enye ide yemfuneko kudaka, ifuna ukukwazi ukusebenzisa i-150000cps.Ngaphezu koko, i-HPMC yeyona ndima ibalulekileyo yokugcina amanzi, ilandelwa kukujiya.Kwi-Skim coat, ngokude nje ukugcinwa kwamanzi kulungile, i-viscosity iphantsi (7-80000), kunokwenzeka kwakhona, ngokuqinisekileyo, i-viscosity inkulu, ukugcinwa kwamanzi okuhambelanayo kungcono, xa i-viscosity ingaphezulu kwe-100. amawaka, i-viscosity yokugcinwa kwamanzi ayikho kakhulu.

Zeziphi ezona zalathisi zingundoqo ze-hydroxypropyl methyl cellulose (HPMC)?

Impendulo: Umxholo we-Hydroxypropyl kunye ne-viscosity, abaninzi abasebenzisi bayayikhathalela ezi zikhombisi zimbini.Umxholo weHydroxypropyl uphezulu, ukugcinwa kwamanzi ngokuqhelekileyo kungcono.I-Viscosity, ukugcinwa kwamanzi, isihlobo (kodwa asiyiyo ngokupheleleyo) nayo ingcono, kunye ne-viscosity, udaka lwesamente lungcono ukusebenzisa ezinye.

IHydroxypropyl methyl cellulose (HPMC) zeziphi ezona zixhobo ziphambili?

Impendulo: i-hydroxypropyl methyl cellulose (HPMC) eyona nto iphambili: i-cotton ecocekileyo, i-chloromethane, i-propylene oxide, ezinye izinto eziluhlaza, i-tablet alkali, i-asidi, i-toluene, i-alcohol isopropyl kunye nokunye.

HPMC in Skim idyasi kwisicelo, indima ephambili, nokuba imichiza?

Impendulo: I-HPMC kwi-Skim coat, ukuqina, amanzi kunye nokwakhiwa kweendima ezintathu.Ukutyeba: i-cellulose inokugqithwa ukuze inqunyanyiswe, ukuze isisombululo sihlale sifana phezulu nasezantsi indima ye-anti-flow ejingayo.Ukugcinwa kwamanzi: yenza i-Skim coat yome kancinci, i-calcium encedisayo engwevu kwisenzo sokusabela kwamanzi.Ukwakhiwa: i-cellulose lubrication, inokwenza i-Skim coat inokwakhiwa okulungileyo.I-HPMC ayithathi nxaxheba kuyo nayiphi na intshukumo yeekhemikhali, kodwa idlala indima exhasayo kuphela.Idyasi ye-Skim kunye namanzi, eludongeni, kukusabela kweekhemikhali, ngenxa yokuveliswa kwezinto ezintsha, udonga lwe-Skim coat phantsi eludongeni, lugaywe lube ngumgubo, kwaye lusebenzise, ​​alulunganga, kuba luye lwaqulunqa into entsha. (icalcium carbonate).Amacandelo aphambili egrey calcium powder ngala: Ca(OH)2, CaO kunye nomlinganiselo omncinci weCaCO3 umxube, CaO+H2O=Ca(OH)2 – Ca(OH)2+CO2=CaCO3↓+H2O grey calcium emanzini. kunye nomoya phantsi kwesenzo se-CO2, ukubunjwa kwe-calcium carbonate, kunye ne-HPMC kuphela amanzi, i-gray encedisayo ye-calcium yokusabela ngcono, eyayo ayizange ithathe inxaxheba kuyo nayiphi na impendulo.

HPMC is non-ionic cellulose ether, ngoko yintoni non-ionic?

IMPENDULO: Ngokuqhelekileyo, iinon-ion zizinto ezingenayo i-ayoni emanzini.Ionization kukuchithwa kwe-electrolyte ibe yi-ion ehlawuliswayo yamahhala kwi-solvent ethile, njengamanzi okanye utywala.Ngokomzekelo, ityuwa esiyidlayo yonke imihla - i-sodium chloride (NaCl) inyibilika emanzini kwaye i-ionizes ukuvelisa i-ion ye-sodium ehambayo yamahhala (Na +) kunye nentlawulo efanelekileyo kunye ne-chloride ions (Cl) enentlawulo embi.Oko kukuthi, i-HPMC emanzini ayidibanisi kwii-ion ezihlawuliswayo, kodwa zikhona njengeemolekyuli.

Yintoni ubushushu be-gelation ye-hydroxypropyl methyl cellulose enxulumene nayo?

Impendulo: Ubushushu bejel ye-HPMC bunxulumene nomxholo we-methoxyl.Umgangatho ophantsi we-methoxyl, uphezulu ubushushu bejeli.

I-Skim coat powder kunye ne-HPMC akukho budlelwane?

Impendulo: I-Skim coat drop powder ngokuyinhloko kunye nomgangatho we-ash calcium unobudlelwane obukhulu kakhulu, kwaye i-HPMC ayinalo ubudlelwane obukhulu kakhulu.Umxholo ophantsi we-calcium we-gray calcium kunye nomlinganiselo ongafanelekanga we-CaO kunye ne-Ca (OH) 2 kwi-gray calcium iya kubangela ukuhla kwepowder.Ukuba kukho ubudlelwane kunye ne-HPMC, ke ukugcinwa kwamanzi okungahambi kakuhle kwe-HPMC kuya kubangela ukulahlekelwa ngumgubo.

Yintoni umahluko phakathi kwamanzi abandayo anyibilikayo kunye ne-soluble hydroxypropyl methyl cellulose kwinkqubo yokuvelisa?

– Impendulo :Amanzi abandayo e-HPMC yohlobo lwesisombululo esikhawulezileyo emva konyango lomphezulu we-glyoxal, afakwe emanzini abandayo asasazwe ngokukhawuleza, kodwa anganyibiliki ngokwenene, i-viscosity phezulu, iyachithwa.Uhlobo lwe-thermosoluble aluzange luphathwe nge-glyoxal.Isixa se-glyoxal sikhulu, ukusabalalisa ngokukhawuleza, kodwa i-viscosity iyacotha, isixa sincinci, ngokuchaseneyo.

Yintoni malunga ne-hydroxypropyl methyl cellulose (HPMC) enukayo?

– Impendulo: I-HPMC eveliswe ngendlela ye-solvent yenziwe nge-toluene kunye ne-isopropyl alcohol.Ukuba ukuhlamba akukuhle kakhulu, kuya kubakho incasa eseleyo.

Ukusetyenziswa okwahlukeneyo, ungayikhetha njani i-hydroxypropyl methyl cellulose (HPMC) efanelekileyo?

- impendulo: yiba nesithukuthezi ngokusetyenziswa komgubo womntwana: imfuno iphantsi, i-viscosity 100000, ok, kubalulekile ukukhusela amanzi ukuba asondele.Ukusetyenziswa kodaka: iimfuno eziphezulu, iimfuno eziphezulu ze-viscosity, i-150000 ukuba ibe ngcono.Ukusetyenziswa kweglue: imfuno yeemveliso ezikhawulezayo, i-viscosity ephezulu.

Leliphi elinye igama le-hydroxypropyl methyl cellulose?

– IMPENDULO: I-Hydroxypropyl MethylCellulose, efinyeziweyo njenge-HPMC okanye i-MHPC, okanye i-Hydroxypropyl Methyl Cellulose;i-cellulose hydroxypropyl methyl ether;I-Hypromellose, iSelulosi, i-2-hydroxypropyl methyl Cellulose ether.

I-HPMC ekusebenziseni idyasi ye-Skim, sisiphi isizathu se-Skim coat bubble?

Impendulo: I-HPMC kwi-Skim coat, ukuqina, amanzi kunye nokwakhiwa kweendima ezintathu.Ukungathathi nxaxheba kuyo nayiphi na impendulo.Iimbangela zamaqamza: 1, amanzi amaninzi.I-2, i-bottom ayomile, phezu kwe-scraping layer, nayo ilula ukuba i-blister.

Udonga lwangaphakathi nangaphandle ifomula yedyasi yeSkim?

- impendulo: udonga lwangaphakathi Ingubo ye-Skim : i-calcium 800KG grey calcium 150KG (i-starch ether, eluhlaza ecocekileyo, i-peng runtu, i-citric acid, i-polyacrylamide inokongezwa ngokufanelekileyo)

Udonga lwangaphandle Idyasi yeSkim : isamente 350KG calcium 500KG isanti yequartz 150KG latex powder 8-12kg cellulose ether 3KG starch ether 0.5kg wood fiber 2KG

Yintoni umahluko phakathi kwe-HPMC kunye ne-MC?

– Impendulo :MC yi-methyl cellulose, eyenziwe nge-cellulose ether ngoluhlu lweempendulo kunye ne-methane chloride njenge-etherifying agent emva kokuba umqhaphu ocociweyo uphathwe nge-alkali.Ngokuqhelekileyo, iqondo lokutshintshwa yi-1.6 ~ 2.0, kwaye ukunyibilika kuyahluka kunye neqondo lokutshintshwa.Yeye-nonionic cellulose ether.

(1) Ukugcinwa kwamanzi kwi-methyl cellulose kuxhomekeke kwisixa sokongeza, i-viscosity, i-particle fineness kunye neqondo lokuchithwa.Ngokubanzi yongeza isixa esikhulu, i-fineness encinci, i-viscosity, izinga lokugcinwa kwamanzi liphezulu.Phakathi kwabo, isixa sokongeza sinempembelelo enkulu ekugcinweni kwamanzi, kwaye i-viscosity ayilingani nokugcinwa kwamanzi.Isantya sokuchithwa sixhomekeke ikakhulu kwiqondo lokuguqulwa komphezulu kunye ne-particle fineness yamasuntswana e-cellulose.Kwezi zingentla ze-cellulose ethers, i-methyl cellulose kunye ne-hydroxypropyl methyl cellulose izinga lokugcinwa kwamanzi liphezulu.

(2) I-Methyl cellulose iyanyibilika emanzini abandayo, okunzima ukuyinyibilika emanzini ashushu.Isisombululo saso samanzi sizinzile kakhulu ngaphakathi kwe-pH = 3 ~ 12.Inokuhambelana kakuhle nestatshi, i-guanidine gum kunye nee-surfactants ezininzi.I-Gelation iyenzeka xa iqondo lokushisa lifikelela kwiqondo lokushisa.

(3) Ukutshintsha kweqondo lobushushu kuyakuchaphazela kakhulu izinga lokugcinwa kwamanzi kwi-methyl cellulose.Ngokuqhelekileyo, okukhona ubushushu buphezulu, kokukhona ukugcinwa kwamanzi kubi.Ukuba ubushushu bodaka bungaphezulu kwe-40℃, ukugcinwa kwamanzi kwi-methyl cellulose kuya kuba kubi kakhulu, okuchaphazela ngokunzulu ukwakhiwa kodaka.

(4) I-Methyl cellulose inefuthe elicacileyo ekwakhiweni kunye nokunamathela kodaka."Ukunamathela" apha kubhekiselele ekunamatheleni okuvakalelwa ngumsebenzi phakathi kwesixhobo kunye ne-substrate eludongeni, oko kukuthi ukuxhathisa kwe-shear yodaka.Ukubambelela kukhulu, ukuxhathisa kwe-shear yodaka kukhulu, amandla afunwa ngabasebenzi kwinkqubo yokusetyenziswa nawo mkhulu, kwaye ukwakhiwa kodaka kubi.Kwiimveliso ze-cellulose ether, i-adhesion ye-methyl cellulose ikwinqanaba eliphakathi.

I-HPMC i-hydroxypropyl methyl cellulose, isulungekiswa ngumqhaphu emva konyango lwe-alkali, kunye ne-propylene oxide kunye ne-chloromethane njenge-ejenti ye-etherifying, ngoluhlu lweempendulo kwaye zenziwe nge-non-ionic cellulose exutywe i-ether.Iqondo lokutshintshwa ngokubanzi yi-1.2 ~ 2.0.Iipropati zayo ziyahluka kunye nomlinganiselo we-methoxy kunye ne-hydroxypropyl content.

(1) IHydroxypropyl methyl cellulose inyibilika ngokulula emanzini abandayo, ekunzima ukuyinyibilika emanzini ashushu.Nangona kunjalo, ubushushu bayo be-gelation kumanzi ashushu ngokucacileyo bungaphezulu kwe-methyl cellulose.I-solubility ye-methyl cellulose emanzini abandayo nayo yaphuculwa kakhulu.

(2) I-viscosity ye-hydroxypropyl methyl cellulose inxulumene nobunzima bayo be-molecular, kwaye ukuphakama kwe-molecular weight, iphezulu i-viscosity.Ubushushu bukwachaphazela i-viscosity.I-Viscosity iyancipha njengoko ubushushu bukhula.Kodwa i-viscosity yayo ifuthe eliphezulu lobushushu liphantsi kune-methyl cellulose.Isisombululo sizinzile xa sigcinwe kwiqondo lokushisa.

(3) I-Hydroxypropyl methyl cellulose izinzile kwi-asidi kunye nesiseko, kwaye isisombululo sayo samanzi sizinzileyo kakhulu kwi-pH = 2 ~ 12.I-Caustic soda kunye namanzi e-lime anempembelelo encinci kwiipropati zayo, kodwa i-alkali inokukhawulezisa izinga lokuchithwa kwayo kunye nokuphucula i-viscosity.I-Hydroxypropyl methyl cellulose izinzile kwiityuwa ngokubanzi, kodwa xa ukuxinwa kwesisombululo setyuwa kuphezulu, i-viscosity yesisombululo se-hydroxypropyl methyl cellulose ithande ukunyuka.

(4) Ukugcinwa kwamanzi e-hydroxypropyl methyl cellulose kuxhomekeke kwidosi kunye ne-viscosity, kwaye izinga lokugcinwa kwamanzi e-hydroxypropyl methyl cellulose liphezulu kunelo le-methyl cellulose kwidosi enye.

(5) I-Hydroxypropyl methyl cellulose inokuxutywa kunye neekhompawundi ze-polymer ezinyibilikayo emanzini ukuze zibe yinto efanayo, isisombululo esiphezulu se-viscosity.Okufana ne-polyvinyl alcohol, i-ether yesitatshi, iglue yemifuno njalo njalo.

(6) Ukunamathela kwe-hydroxypropyl methyl cellulose kulwakhiwo lodaka kuphezulu kune-methyl cellulose.

(7) I-Hydroxypropyl methyl cellulose inokumelana ne-enzyme engcono kune-methyl cellulose, kunye nesisombululo sayo sokutshatyalaliswa kwe-enzyme yesisombululo singaphantsi kune-methyl cellulose.

Yintoni ekufuneka iqwalaselwe kwisicelo esisebenzayo malunga nobudlelwane phakathi kwe-viscosity kunye nobushushu be-HPMC?

Impendulo: I-viscosity ye-HPMC ihambelana ngokungafaniyo neqondo lokushisa, oko kukuthi, i-viscosity iyanda ngokuhla kweqondo lokushisa.Xa sithetha nge-viscosity yemveliso, sithetha malunga ne-viscosity ye-2% yemveliso emanzini kwi-20 degrees Celsius.

Kwisicelo esisebenzayo, kwiindawo ezinomahluko omkhulu wokushisa phakathi kwehlobo kunye nobusika, kufuneka kuqatshelwe ukuba kucetyiswa ukuba kusetyenziswe i-viscosity ephantsi kakhulu ebusika, ehambelana nokwakhiwa.Ngaphandle koko, xa iqondo lokushisa liphantsi, i-viscosity ye-cellulose iya kwanda, kwaye xa ukhuhla, ukuvakalelwa kuya kuba nzima.

I-viscosity ephakathi : 75000-100000 ikakhulu isetyenziselwa i-putty

Isizathu: Ukugcinwa kakuhle kwamanzi

I-viscosity ephezulu: i-HPMC 150000-200000 isetyenziswa ikakhulu kwi-polystyrene yamasuntswana e-insulation udaka lweglu imathiriyeli yomgubo kunye ne-vitrified beads yokugquma udaka.

Isizathu: i-viscosity ephezulu, udaka alulula ukulahla, ukuhamba ukuxhoma, ukuphucula ukwakhiwa.

Kodwa xa sithetha ngokubanzi, i-viscosity ephezulu, ngcono ukugcinwa kwamanzi, iifektri ezininzi zodaka olomileyo, ngokuqwalasela iindleko, sebenzisa i-medium viscosity HPMC cellulose (75000-100000) ukuba ithathe indawo ye-viscosity ephakathi kunye nephantsi HPMC cellulose (20000-40000) ukunciphisa isixa esongezelelweyo.