Abavelisi be-HPMC bakufundisa ukuvavanya i-viscosity ye-HPMC

Inkampani ye-Tiantai Cellulose igxile kuphando, uphuhliso, ukuveliswa kunye nokukhuthazwa kweentengiso ze-hydroxypropyl methyl cellulose iimveliso ze-HPMC. Ukucoceka kwe-HPMC hydroxypropyl methyl cellulose sesona sihloko sichaphazelekayo semveliso kubavelisi kunye nabasebenzisi. Apha thina hydroxypropyl methyl cellulose abavelisi ukunika intshayelelo eneenkcukacha, ndiyathemba ukufunda ukunceda.

Ukumiselwa kobunyulu be-HPMC hydroxypropyl methyl cellulose

Umgaqo

IHydroxypropyl methyl cellulose HPMC ayinyibiliki kwi-ethanol engama-80%. Emva kokuchithwa kunye nokuhlamba amaxesha amaninzi, i-80% ye-ethanol echithwe kwisampulu iyahlukana kwaye isuswe ukufumana i-hydroxypropyl methyl cellulose ecocekileyo ye-HPMC.

Renomdla

Ngaphandle kokuba kuchazwe ngenye indlela, kuphela ii-reagents eziqinisekisiweyo ukuba zihlalutye kwaye zihlanjululwe ngamanzi ahlambulukileyo okanye ahlanjululweyo okanye amanzi ahlambulukileyo anokuthelekiswa aya kusetyenziswa kuhlalutyo.

I-95% ye-ethanol (GB/T 679).

I-Ethanol, isisombululo se-80%, i-dilute 95% ethanol (E.2.1) 840mL ngamanzi ukuya kwi-1L.

I-BMI (GB/T 12591).

Isixhobo

Izixhobo zaselebhu eziqhelekileyo

Imagnethi yokufudumeza i-stirrer, ubude bentonga eshukumisayo malunga ne-3.5cm.

I-crucible yokucoca, i-40mL, i-aperture 4.5μm ~ 9μm.

Isitya somphezulu weglasi, φ10cm, umngxuma osembindini.

Ibeaker, 400mL.

Ukufudumala rhoqo ukuhlamba amanzi.

I-oveni, inokulawula ubushushu kwi-105℃±2℃.

Inkqubo

Ngokuchanekileyo isampuli 3g (echaneke ukuya 0.001g) kwibhekile ubunzima rhoqo, yongeza 150mL 80% ethanol kwi 60 ℃ ~ 65 ℃, faka intonga kazibuthe kwimagnethi ukufudumeza izivusi, gquma isitya umphezulu, ufake ithemometha embindini. umngxuma, vula izixhobo zokufudumeza, lungisa isantya sokuzamisa ukunqanda ukuchaphaza, kwaye ugcine ubushushu bukwindawo 60℃ ~ 65℃. Ukuvuselela i-10 min.

Yeka ukushukumisa, beka ibhekile kwindawo yokuhlambela yamanzi obushushu obungaguqukiyo obuyi-60℃ ~ 65℃, yima ngxi ukulungisa into enganyibilikiyo, kwaye ugalele ulwelo olunamandla amakhulu kangangoko kunokwenzeka kwicrucible yobunzima bokucoca.

Yongeza i-ethanol eyi-150mL 80% kwi-60℃ ~ 65℃ kwibeaker, phinda olu sebenziso lungasentla lokuvuselela nokucoca, kwaye emva koko uhlambe i-beaker, isitya esingaphezulu, intonga eshukumisayo kunye nethemometha ngononophelo nge-80% ethanol ku-60℃ ~ 65℃, ukuze umbandela onganyibilikiyo ugqithiselwa ngokupheleleyo kwi-crucible, kwaye uhlambe ngakumbi iziqulatho ye crucible. Ukufunxa kufuneka kusetyenziswe ngexesha lo msebenzi kwaye ukomiswa kwekhekhe kufuneka kugwenywe. Ukuba amasuntswana adlula kwisihluzi, ukufunxa kufuneka kuthotywe.

Qaphela: kufuneka kuqinisekiswe ukuba i-sodium chloride kwisampuli ihlanjwe ngokupheleleyo yi-80% ye-ethanol. Ukuba kuyimfuneko, i-0.1mol / L isisombululo se-nitrate yesilivere kunye ne-6mol / L ye-nitric acid ingasetyenziselwa ukujonga ukuba i-filtrate iqukethe i-chloride ion.

Kwiqondo lokushisa lokushisa, iziqulatho ze-crucible zihlanjwe kabini nge-95% ethanol kwi-50mL, kwaye ekugqibeleni nge-ethyl mi20mL yokuhlamba okwesibini. Ixesha lokuhluza akufuneki libe lide kakhulu. I-crucible yafakwa kwi-beaker kwaye yafudumeza kwibhafu yomphunga de akukho vumba le-ethyl mi lifunyenwe.

Qaphela: ukuhlamba nge-ethyl mi kuyimfuneko ukususa ngokupheleleyo i-ethanol kwi-insoluble substance. Ukuba i-ethanol ayisuswanga ngokupheleleyo ngaphambi kokumisa i-oven, ukususa ngokupheleleyo akunakwenzeka ngexesha lokumisa i-oven.

I-crucible kunye ne-beaker zafakwa kwi-oven kwi-105 ℃ ± 2 ℃ yokomisa i-2h, emva koko idluliselwe kwi-dryer ukupholisa i-30min kwaye ilinganiswe, kwaye yomiswa nge-1h kwaye ilinganiswe ukupholisa de utshintsho lobunzima alukho ngaphezu kwe-0.003g . Kwimeko yokwanda kobunzima ngexesha lokumisa kwe-1h, obona bunzima bujongwayo buphantsi buya kubakhona.

Iziphumo zibaliwe

Ukucoceka kwe-HPMC hydroxypropyl methyl cellulose kubalwe njengeqhezu lobunzima P, kwaye ixabiso libonakaliswe njenge-%

I-M1 - ubunzima bezinto ezomileyo ezingenayo i-insoluble, kwiigram (g);

I-M0 - Ubuninzi becandelo lokuvavanya, kwiigram (g);

I-W0 - Umswakama kunye nomxholo oguqukayo wesampuli,%.

Ixabiso le-arithmetic ye-arithmetic yemilinganiselo emibini ehambelanayo iyancitshiswa ukuya kwindawo enye yedesimali njengesiphumo somlinganiselo.

Pulungiso

Umahluko opheleleyo phakathi kwemilinganiselo emibini ezimeleyo efunyenwe phantsi kweemeko zokuphindaphinda awukho mkhulu kune-0.3%, ngaphandle kokuba ngaphezulu kwe-0.3% ayidluli kwi-5%.

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Ixesha lokuposa: Feb-14-2022