HPMC VS HEC: 6 Umahluko Kufuneka Uyazi!

Yazisa:

I-Hydroxypropylmethylcellulose (HPMC) kunye ne-hydroxyethylcellulose (HEC) zombini izongezo ezisetyenziswa ngokuqhelekileyo kumashishini okutya, e-cosmetic kunye namayeza. Ezi zinto ziphuma kwi-cellulose zinethemba elibanzi losetyenziso ngenxa yokunyibilika kwazo okukhethekileyo kwamanzi, ukuzinza kokuqina, kunye nobuchule obugqwesileyo bokwenza ifilimu.

1.Ulwakhiwo lwekhemikhali:

I-HPMC yipolymer eyenziweyo evela kwiselulosi. Yenziwe ngokuguqula iikhemikhali zeselulosi yendalo ngokongeza ipropylene oxide kunye nemethyl chloride. I-HEC ikwaluhlobo lwe-cellulose derivative, kodwa yenziwa ngokusabela i-cellulose yendalo kunye ne-ethylene oxide kwaye emva koko iphathwa nge-alkali.

2. Ukunyibilika:

Zombini i-HPMC kunye ne-HEC zinyibilika emanzini kwaye zinokunyibilika emanzini abandayo. Kodwa i-solubility ye-HEC ingaphantsi kune-HPMC. Oku kuthetha ukuba i-HPMC ine-dispersibility engcono kwaye ingasetyenziswa ngokulula kwimixube.

3. I-Viscosity:

I-HPMC kunye ne-HEC zineempawu ezahlukeneyo ze-viscosity ngenxa yezakhiwo zazo zeekhemikhali. I-HEC inobunzima obuphezulu bemolekyuli kunye nesakhiwo esixineneyo kune-HPMC, enika i-viscosity ephezulu. Ngoko ke, i-HEC isetyenziswa rhoqo njenge-thickener kwiifom ezifuna i-viscosity ephezulu, ngelixa i-HPMC isetyenziselwa ukwakheka okudinga i-viscosity ephantsi.

4. Ukwenza ifilimu:

Zombini i-HPMC kunye ne-HEC zinobuchule obubalaseleyo bokwenza ifilimu. Kodwa i-HPMC inobushushu obuphantsi bokwenza ifilim, okuthetha ukuba ingasetyenziswa kumaqondo obushushu asezantsi. Oku kwenza i-HPMC ifaneleke ngakumbi ukusetyenziswa kwimixube efuna amaxesha omisa ngokukhawuleza kunye nokuncamathela okungcono.

5. Uzinzo:

I-HPMC kunye ne-HEC zizinzile phantsi kweemeko ezininzi ze-pH kunye nobushushu. Nangona kunjalo, i-HEC ivakalelwa ngakumbi kwiinguqu ze-pH kune-HPMC. Oku kuthetha ukuba i-HEC kufuneka isetyenziswe ekuxutyweni kunye noluhlu lwe-pH ye-5 ukuya kwi-10, ngelixa i-HPMC ingasetyenziswa kuluhlu olubanzi lwe-pH.

6. Isicelo:

Iimpawu ezahlukeneyo ze-HPMC kunye ne-HEC zibenza zilungele izicelo ezahlukeneyo. I-HEC isetyenziswa ngokuqhelekileyo njenge-ejenti yokuqina kwi-cosmetic kunye ne-pharmaceulation formulations. Ikwasetyenziswa njenge-binder kunye ne-agent-forming agent kwi-tablet formulations. I-HPMC isetyenziswa njenge-thickener, stabilizer, kunye ne-film-forming agent ekutyeni, kwiziyobisi, nakwi-cosmetic formulations. Ikwasetyenziswa njenge-agent ye-gelling kwezinye izicelo zokutya.

Ukuququmbela:

I-HPMC kunye ne-HEC zombini i-cellulose derivatives eneempawu ezizodwa ezifanelekileyo kwizicelo ezahlukeneyo. Ukuqonda umahluko phakathi kwezi zongezo zimbini kunokukunceda ukhethe eyona ilungileyo kwiresiphi yakho. Lilonke, i-HPMC kunye ne-HEC zizongezo ezikhuselekileyo nezisebenzayo ezibonelela ngeenzuzo ezininzi kumashishini okutya, ezokuthambisa kunye namayeza.