I-Carboxymethylcellulose (CMC) ithathwa njengekhuselekile ukusetyenziswa kumashishini ahlukeneyo, kubandakanywa nokutya kunye namacandelo amayeza, apho isetyenziswa kakhulu. Le derivative ye-cellulose enyibilikayo emanzini iye yavavanywa ngokuqatha kunye novavanyo ukuze kuqinisekiswe ukhuseleko lwayo kwimpilo yabantu kunye nokusingqongileyo. Kule ngxoxo ebanzi, sihlolisisa imiba yokhuseleko lwe-carboxymethylcellulose, sihlola isimo sayo sokulawula, iziphumo ezinokuthi zibe nezempilo, ukuqwalaselwa kokusingqongileyo, kunye neziphumo zophando ezifanelekileyo.
Ubume boLawulo:
I-Carboxymethylcellulose yamkelwe ukuba isetyenziswe ngabasemagunyeni emhlabeni jikelele. E-United States, uLawulo lokuTya kunye neDrugs (i-FDA) luchonge i-CMC njengeyona nto eyaziwa ngokuba iKhuselekileyo (GRAS) xa isetyenziswa ngokuhambelana neendlela ezilungileyo zokuvelisa. Ngokufanayo, i-European Food Safety Authority (EFSA) iye yavavanya i-CMC kwaye yaseka ixabiso elamkelekileyo lemihla ngemihla (ADI), iqinisekisa ukhuseleko lwayo lokusetyenziswa.
Kumayeza kunye nezithambiso, i-CMC isetyenziswa ngokubanzi, kwaye ukhuseleko lwayo lusekwe ngokuthobela izikhokelo zolawulo. Ihambelana nemigangatho ye-pharmacopeial, iqinisekisa ukufaneleka kwayo ukusetyenziswa kwimiqulu yeyeza.
Ukhuseleko kwiiMveliso zoKutya:
1. Izifundo zeToxicological:
Uphononongo olubanzi lwetyhefu luye lwenziwa ukuvavanya ukhuseleko lweCMC. Olu phononongo lubandakanya uphononongo lwetyhefu ebukhali kunye nengapheliyo, i-mutagenicity, i-carcinogenicity, kunye netyhefu yokuzala kunye nophuhliso. Iziphumo zihlala zixhasa ukhuseleko lwe-CMC kumanqanaba osetyenziso amiselweyo.
2. UkuThatha iMihla okwamkelekileyo (ADI):
Amaqumrhu alawulayo amisela amaxabiso e-ADI ukuseka ubungakanani bento enokuthi isetyenziswe yonke imihla kubomi bonke ngaphandle komngcipheko wempilo oncomekayo. I-CMC ine-ADI esekiweyo, kwaye ukusetyenziswa kwayo kwiimveliso zokutya kungaphantsi kwamanqanaba athathwa njengekhuselekile.
3. Ukwalana:
I-CMC ngokuqhelekileyo ithathwa njenge-non-allergenic. I-allergies kwi-CMC inqabile kakhulu, iyenza ibe sisithako esifanelekileyo kubantu abanobuthathaka obahlukeneyo.
4. Ukwetyisa:
I-CMC ayetyiswa okanye ayifunxekisiweyo kwindlela yesisu somntu. Idlula kwisixokelelwano sokugaya ubukhulu becala ingatshintshanga, igalelo kwiprofayili yayo yokhuseleko.
Ukhuseleko kuMachiza kunye neZithambiso:
1. I-Biocompatibility:
Kuqulunqo lwamayeza kunye nezithambiso, i-CMC ixabiswa ngenxa yokuhambelana kwayo kwezinto eziphilayo. Ukunyamezela kakuhle kwesikhumba kunye neembrane ze-mucous, okwenza kube yinto efanelekileyo yokusetyenziswa kwiinkqubo ezahlukeneyo zomlomo kunye nomlomo.
2. Uzinzo:
I-CMC inegalelo kuzinzo lokuqulunqwa kwamayeza, inceda ukugcina ingqibelelo kunye nokusebenza kakuhle kwamayeza. Ukusetyenziswa kwayo kuxhaphake ekumisweni komlomo, apho inceda ekukhuseleni ukuhlaliswa kweengqungquthela eziqinileyo.
3. Ukusetyenziswa kwamehlo:
I-CMC iqhele ukusetyenziswa kwizisombululo zamehlo kunye namathontsi eliso ngenxa yokukwazi ukunyusa i-viscosity, ukuphucula ukugcinwa kwe-ocular, kunye nokuphucula ukusebenza konyango lokuqulunqwa. Ukhuseleko lwayo kwezi zicelo luxhaswa yimbali yayo ende yokusetyenziswa.
Iingqwalasela zokusiNgqongileyo:
1. I-Biodegradability:
I-Carboxymethylcellulose ithathwe kwimithombo yendalo yeselulosi kwaye i-biodegradable. Ifumana ukubola yi-microorganisms kwindalo, igalelo kwiprofayili yayo eco-friendly.
2. Ubutyhefu basemanzini:
Uphononongo oluvavanya ubutyhefu basemanzini be-CMC lubonise ngokubanzi ubutyhefu obuphantsi kwizinto eziphila emanzini. Ukusetyenziswa kwayo ekuqulunqweni okusekelwe emanzini, njengepeyinti kunye ne-detergents, akuhambelani nomonakalo omkhulu wendalo.
Iziphumo zoPhando kunye neendlela ezisakhulayo:
1. Uncedo oluZinzileyo:
Njengoko imfuno ezinzileyo kunye nezinto ezihambelana nokusingqongileyo ikhula, kukho umdla owongeziweyo ekufumaneni okuzinzileyo kwemathiriyeli ekrwada yemveliso yeCMC. Uphando lujolise ekwandiseni iinkqubo zokutsalwa kunye nokuhlola enye imithombo ye-cellulose.
2. Izicelo zeNanocellulose:
Uphando oluqhubekayo luphanda ukusetyenziswa kwe-nanocellulose, ephuma kwimithombo ye-cellulose kuquka i-CMC, kwizicelo ezahlukeneyo. I-Nanocellulose ibonisa iipropati ezizodwa kwaye inokufumana izicelo kwiinkalo ezifana ne-nanotechnology kunye nophando lwe-biomedical.
Isiphelo:
I-Carboxymethylcellulose, kunye neprofayili yokhuseleko olusekiweyo, isithako esiphambili kumashishini ahlukeneyo, kubandakanya ukutya, amayeza, izithambiso, iingubo, kunye nokunye. Ulwamkelo lolawulo, izifundo ezibanzi zetoxicological, kunye nembali yokusetyenziswa ngokukhuselekileyo iqinisekisa ukufaneleka kwayo kuluhlu olubanzi lwezicelo. Njengoko amashishini aqhubeka nokuguquka, ukhuseleko kunye nokuzinza kwezinto eziphathekayo zizinto eziphambili, kwaye i-carboxymethylcellulose ihambelana nale mikhwa.
Ngelixa i-CMC ngokubanzi ithathwa njengekhuselekile, abantu abanengxaki yokwalana okanye ukuva izinto ezithile kufuneka badibane noochwephesha bezempilo okanye abaqaphi ukuba banenkxalabo malunga nokusetyenziswa kwayo. Njengoko ukuqhubela phambili kophando kunye nezicelo ezitsha zivela, intsebenziswano eqhubekayo phakathi kwabaphandi, abavelisi, kunye nezigqeba ezilawulayo ziya kuqinisekisa ukuba i-CMC iyaqhubeka nokuhlangabezana nemigangatho ephezulu yokhuseleko kunye nokusebenza kakuhle. Ngamafutshane, i-carboxymethylcellulose licandelo elikhuselekileyo nelixabisekileyo elinegalelo ekusebenzeni kunye nomgangatho weemveliso ezininzi, idlala indima ebalulekileyo kwizicelo ezahlukeneyo kwimarike yehlabathi.
Ixesha lokuposa: Jan-04-2024