Ngaba i-HPMC i-hydrophobic okanye i-hydrophilic?

IHydroxypropyl methylcellulose (HPMC) yipolymer eguquguqukayo enezo zombini iipropathi ze-hydrophobic kunye ne-hydrophilic, iyenza ibe yodwa kwiintlobo ngeentlobo zezicelo kumashishini ahlukeneyo.Ukuze siqonde i-hydrophobicity kunye ne-hydrophilicity ye-HPMC, kufuneka sifunde isakhiwo sayo, iipropati kunye nokusetyenziswa ngokunzulu.

Ubume be-hydroxypropyl methylcellulose:

I-HPMC iphuma kwi-cellulose, ipholima yendalo efumaneka kwiindonga zeeseli zezityalo.Ukuguqulwa kweselulosi kubandakanya ukuqaliswa kwe-hydroxypropyl kunye namaqela e-methyl kumqolo we-cellulose.Olu hlengahlengiso lutshintsha iipropathi zepolymer, lunikezela ngeempawu ezithile eziluncedo kuluhlu olubanzi lwezicelo.

I-Hydrophilicity ye-HPMC:

IHydroxy:

I-HPMC iqulethe amaqela e-hydroxypropyl kwaye i-hydrophilic.La maqela e-hydroxyl anobudlelwane obuphezulu kwiimolekyuli zamanzi ngenxa yokudibanisa i-hydrogen.

Iqela le-Hydroxypropyl linokwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi, okwenza i-HPMC inyibilike emanzini ukuya kumlinganiselo othile.

I-methyl:

Ngelixa iqela le-methyl linegalelo kwi-hydrophobicity yonke ye-molecule, ayichasananga ne-hydrophilicity yeqela le-hydroxypropyl.

Iqela le-methyl lilingana ne-non-polar, kodwa ubukho beqela le-hydroxypropyl limisela umlingiswa we-hydrophilic.

I-Hydrophobicity ye-HPMC:

I-methyl:

Amaqela e-methyl kwi-HPMC amisela ukuya kuthi ga kwinqanaba elithile le-hydrophobicity yayo.

Nangona ingeyiyo i-hydrophobic njengeepolima zokwenziwa ngokupheleleyo, ubukho bamaqela e-methyl kunciphisa i-hydrophilicity iyonke ye-HPMC.

Iimpawu zokwenza ifilimu:

I-HPMC yaziwa ngeempawu zayo zokwenza ifilim kwaye isoloko isetyenziswa kumachiza kunye nezicelo zokuthambisa.I-Hydrophobicity igalelo ekwenziweni kwefilimu ekhuselayo.

Ukudibana nezinto ezingezizo ipolar:

Kwezinye izicelo, i-HPMC inokunxibelelana nezinto ezingekho kwi-polar ngenxa ye-hydrophobicity yayo.Le propati ibalulekile kwiinkqubo zokuhanjiswa kwamachiza kwishishini loxubo-mayeza.

Usetyenziso lwe-HPMC:

iyeza:

I-HPMC isetyenziswa ngokubanzi kuqulunqo lwamayeza njengesibophelelo, ifilimu yangaphambili, kunye nesilungisi se-viscosity.Isakhono sayo sokwenza ifilim sinceda ukukhululwa okulawulwayo kwamachiza.

Isetyenziswa ngomlomo kwiifom zedosi eqinileyo efana neetafile kunye neecapsules.

Ishishini lokwakha:

Kwicandelo lokwakha, i-HPMC isetyenziswa kwiimveliso ezisekwe kwisamente ukuphucula ukusebenza, ukugcinwa kwamanzi kunye nokuncamathela.

I-Hydrophilicity inceda ukugcina amanzi, ngelixa i-hydrophobicity inceda ukuphucula ukunamathela.

ishishini lokutya:

I-HPMC isetyenziswa njengento etyebisayo kunye nejeli kushishino lokutya.Ubume bayo be-hydrophilic bunceda ukwenza iigels ezizinzileyo kunye nokulawula i-viscosity yeemveliso zokutya.

izithambiso:

Kwizinto zokuthambisa, i-HPMC isetyenziswa kwiimveliso ezifana neekhrimu kunye nezinto zokuthambisa ngenxa yeempawu zayo zokwenza ifilim kunye nokujiya.

I-Hydrophilicity iqinisekisa ukumanzisa kakuhle kolusu.

ukuququmbela:

HPMC yi polima ukuba zombini hydrophilic kunye hydrophobic.Ibhalansi phakathi kwe-hydroxypropyl kunye namaqela e-methyl kwisakhiwo sayo inika ukuguquguquka okukhethekileyo, okukuvumela ukuba ube noluhlu olubanzi lwezicelo.Ukuqonda ezi propati kubalulekile ekulungiseleleni i-HPMC kusetyenziso oluthile kumashishini ahlukeneyo, apho ukukwazi kwe-HPMC ukusebenzisana namanzi kunye nezinto ezingekho phantsi zisetyenziselwa iinjongo ezahlukeneyo.