I-HPMC okanye i-hydroxypropyl methylcellulose yinto esetyenziswa kwizinto ezahlukeneyo kumashishini ahlukeneyo aquka amayeza, izinto zokuthambisa kunye nokutya. Isetyenziswa ngokubanzi njenge-thickener kunye ne-emulsifier, kwaye i-viscosity yayo iyatshintsha ngokuxhomekeke kubushushu obuvezwayo. Kweli nqaku, siza kugxila kubudlelwane phakathi kwe-viscosity kunye nobushushu kwi-HPMC.
I-Viscosity ichazwa njengomlinganiselo wokumelana nolwelo ukuba uhambe. I-HPMC yinto ephantse iqine umlinganiselo wayo wokuxhathisa uxhomekeke kwizinto ezahlukeneyo, kuquka ubushushu. Ukuqonda ubudlelwane phakathi kwe-viscosity kunye nobushushu kwi-HPMC, kufuneka kuqala sazi ukuba into yenziwa njani kwaye yenziwe ngantoni.
I-HPMC ithathwe kwi-cellulose, i-polymer ngokwemvelo kwizityalo. Ukuvelisa i-HPMC, i-cellulose kufuneka iguqulwe ngokwekhemikhali ngepropylene oxide kunye ne-methyl chloride. Olu hlengahlengiso luphumela ekwenziweni kwamaqela e-hydroxypropyl kunye ne-methyl ether kwikhonkco le-cellulose. Isiphumo siyinto e-semi-solid enokuthi inyibilike emanzini kunye ne-solvents ye-organic kwaye isetyenziswe kwiintlobo ezahlukeneyo zezicelo, kubandakanywa njengento yokugubungela iipilisi kunye ne-agent agent yokutya, phakathi kwabanye.
I-viscosity ye-HPMC ixhomekeke kugxininiso lwento kunye nobushushu obuvezwayo. Ngokubanzi, i-viscosity ye-HPMC iyancipha ngokunyuka koxinzelelo. Oku kuthetha ukuba ugxininiso oluphezulu lwe-HPMC lukhokelela kwii-viscosities ezisezantsi kwaye ngokuphambeneyo.
Nangona kunjalo, ubudlelwane obuphambeneyo phakathi kwe-viscosity kunye nobushushu bunzima ngakumbi. Njengoko bekutshiwo ngaphambili, i-viscosity ye-HPMC iyanda ngokuhla kweqondo lobushushu. Oku kuthetha ukuba xa i-HPMC iphantsi kobushushu obuphantsi, ukukwazi kwayo ukuhamba kuyancipha kwaye iba yi-viscous ngakumbi. Ngokunjalo, xa i-HPMC iphantsi kobushushu obuphezulu, ukukwazi kwayo ukuhamba kuyanda kwaye i-viscosity yayo iyancipha.
Kukho izinto ezahlukeneyo ezichaphazela ubudlelwane phakathi kobushushu kunye ne-viscosity kwi-HPMC. Ngokomzekelo, ezinye i-solutes ezikhoyo kulwelo zinokuchaphazela i-viscosity, njengoko kunokwenzeka ne-pH yolwelo. Ngokubanzi, nangona kunjalo, kukho ubudlelwane obuphambeneyo phakathi kwe-viscosity kunye neqondo lokushisa kwi-HPMC ngenxa yempembelelo yeqondo lokushisa kwi-hydrogen bonding kunye nokusebenzisana kweemolekyuli zamatyathanga e-cellulose kwi-HPMC.
Xa i-HPMC iphantsi kobushushu obuphantsi, amatyathanga aselulosi abe ngqongqo ngakumbi, nto leyo ekhokelela ekwandeni kwe-hydrogen bonding. Ezi bhondi ze-hydrogen zibangela ukuchasana kwento ukuba kuhambe, ngaloo ndlela kwandisa i-viscosity yayo. Ngokwahlukileyo, xa ii-HPMCs ziphantsi kobushushu obuphezulu, amatyathanga e-cellulose aye aguquguquka ngakumbi, nto leyo eyabangela ukuba kunciphe iibhondi ze-hydrogen. Oku kunciphisa ukuxhathisa kwento ukuhamba, okukhokelela kwi-viscosity ephantsi.
Kuyaphawuleka ukuba nangona ngokuqhelekileyo kukho ubudlelwane obuphambeneyo phakathi kwe-viscosity kunye nobushushu be-HPMC, oku akusoloko kunjalo kuzo zonke iindidi ze-HPMC. Ubudlelwane obuchanekileyo phakathi kwe-viscosity kunye nobushushu bunokwahluka ngokuxhomekeke kwinkqubo yokuvelisa kunye nebakala elithile le-HPMC elisetyenzisiweyo.
I-HPMC yinto enemisebenzi emininzi esetyenziswa kakhulu kumashishini ahlukeneyo ngenxa yokutyeba kunye neempawu zayo zokumisela. I-viscosity ye-HPMC ixhomekeke kwizinto ezininzi, kubandakanywa ukuxinwa kwento kunye nobushushu obuvezwayo. Ngokubanzi, i-viscosity ye-HPMC ihambelana ngokungafaniyo neqondo lokushisa, oku kuthetha ukuba njengoko ubushushu buyancipha, i-viscosity iyanda. Oku kungenxa yefuthe lobushushu kwi-hydrogen bonding kunye nokunxibelelana kweemolekyuli zamatyathanga e-cellulose ngaphakathi kwe-HPMC.
Ixesha lokuposa: Sep-08-2023