ICarbomer kunye ne-hydroxyethylcellulose (HEC) zombini zizithako ezisetyenziswa ngokuqhelekileyo kumashishini ahlukeneyo, ngakumbi kwizinto zokuthambisa, amayeza, kunye neemveliso zokhathalelo lomntu. Ngaphandle kokusetyenziswa kwazo ezifanayo njengee-agent ezityebisayo kunye nezizinzisi, zinemixube eyahlukeneyo yeekhemikhali, iipropathi, kunye nokusetyenziswa.
1. Ukuqulunqwa kwemichiza:
ICarbomer: IiCarbomers zezenziwe iipolima ezinobunzima bemolekyuli ephezulu ye-acrylic acid edityaniswe ne-polyalkenyl ethers okanye i-divinyl glycol. Ngokuqhelekileyo ziveliswa ngokuphendula kwe-polymerization.
I-Hydroxyethylcellulose: I-Hydroxyethylcellulose, kwelinye icala, iphuma kwi-cellulose, i-polymer eyenzeka ngokwemvelo. Iveliswa ngokuphatha i-cellulose nge-sodium hydroxide kunye ne-ethylene oxide ukwazisa amaqela e-hydroxyethyl kwi-cellulose backbone.
2. Ulwakhiwo lweMolekyuli:
I-Carbomer: I-Carbomers ine-branched ye-molecular structure ngenxa yendalo yabo edibeneyo. Le branching inegalelo ekukwazini kwabo ukwenza inethiwekhi ye-three-dimensional xa i-hydrated, ekhokelela ekugqithiseni okusebenzayo kunye neempawu ze-gelling.
I-Hydroxyethylcellulose: I-Hydroxyethylcellulose igcina i-linear structure ye-cellulose, kunye namaqela e-hydroxyethyl adityaniswe kwiiyunithi ze-glucose ecaleni kwekhonkco le-polymer. Esi sakhiwo somgca sichaphazela ukuziphatha kwayo njenge-thickener kunye ne-stabilizer.
3. Ukunyibilika:
ICarbomer: IiCarbomers zihlala zibonelelwa ngohlobo lomgubo kwaye azinyibiliki emanzini. Nangona kunjalo, banokudumba kwaye bafake amanzi kwizisombululo ezinamanzi, zenze iijeli ezibonakalayo okanye i-viscous dispersions.
IHydroxyethylcellulose: IHydroxyethylcellulose ikwabonelelwa ngomgubo kodwa inyibilika lula emanzini. Iyanyibilika ukuze yenze izisombululo ezicacileyo okanye ezincinci, kuxhomekeke kugxininiso kunye namanye amacandelo okuqulunqa.
4. Ukuqinisa iiPropati:
ICarbomer: IiCarbomers zizityebi ezisebenza kakuhle kakhulu kwaye zinokwenza i-viscosity kuluhlu olubanzi lwemixube, kubandakanya iikhrimu, iijeli, kunye nezinto zokuthambisa. Banikezela ngeempawu ezibalaseleyo zokumisa kwaye bahlala besetyenziselwa ukuzinzisa i-emulsions.
IHydroxyethylcellulose: I-Hydroxyethylcellulose ikwasebenza njenge-thickener kodwa ibonisa indlela yokuziphatha eyahlukileyo xa kuthelekiswa nee-carbomers. Inika i-pseudoplastic okanye i-shear-thinning flow to formulations, oku kuthetha ukuba i-viscosity yayo iyancipha phantsi koxinzelelo lwe-shear, iququzelele ukusetyenziswa okulula kunye nokusabalalisa.
5. Ukuhambelana:
ICarbomer: IiCarbomers ziyahambelana noluhlu olubanzi lwezithako zokuthambisa kunye namanqanaba e-pH. Nangona kunjalo, banokufuna i-neutralization kunye ne-alkalis (umzekelo, i-triethanolamine) ukufezekisa ukutyeba kunye neempawu ze-gelling.
IHydroxyethylcellulose: IHydroxyethylcellulose iyahambelana nezinyibilikisi ezahlukeneyo kunye nezithako eziqhelekileyo zokuthambisa. Izinzile phezu koluhlu olubanzi lwe-pH kwaye ayifuni ukungathathi hlangothi ukwenzela ukuqina.
6. IiNdawo zokuSebenza:
ICarbomer: IiCarbomers zifumana ukusetyenziswa okubanzi kwiimveliso zokhathalelo lomntu ezinje ngeekhrimu, iiloshini, iigels, kunye nokwakheka kweenwele. Zikwasetyenziswa kwiimveliso zoxubo-mayeza ezifana neejeli ze-topical kunye nezisombululo ze-ophthalmic.
IHydroxyethylcellulose: IHydroxyethylcellulose idla ngokusetyenziswa kwiindlela zokuthambisa kunye nokhathalelo lomntu siqu, kubandakanywa iishampu, iiconditioners, ukuhlamba umzimba, kunye nentlama yamazinyo. Ikwasetyenziswa kwizicelo zamayeza, ngakumbi kwimixube yezihloko.
7. Iimpawu zovakalelo:
I-Carbomer: Iijeli zeCarbomer zidla ngokubonisa ukuthungwa okugudileyo kunye nokuthambisa, ukunika amava anqwenelekayo oluvo kuqulunqo. Nangona kunjalo, banokuziva bebambekile kancinci okanye bencangathi xa befaka isicelo kwezinye iimeko.
I-Hydroxyethylcellulose: I-Hydroxyethylcellulose inika i-silky ne-non-ncangathi yokuziva kwimixube. Ukuziphatha kwayo kwe-shear-thinning kunegalelo ekusasazekeni lula kunye nokufunxa, kuphucula amava omsebenzisi.
8. Iingqwalasela zoLawulo:
ICarbomer: IiCarbomers zibonwa njengekhuselekile (GRAS) ngabasemagunyeni abalawulayo xa zisetyenziswa ngokuhambelana neendlela ezilungileyo zokuvelisa (GMP). Nangona kunjalo, iimfuno ezithile zolawulo zinokwahluka ngokuxhomekeke kwisicelo esicetywayo kunye nommandla wejografi.
I-Hydroxyethylcellulose: I-Hydroxyethylcellulose ikwagqalwa njengekhuselekile ukuba isetyenziswe kwizinto zokuthambisa kunye namayeza, kunye nemvume yokulawula evela kwabasemagunyeni abafanelekileyo. Ukuthotyelwa kwemimiselo esebenzayo kunye nezikhokelo kubalulekile ekuqinisekiseni ukhuseleko lwemveliso kunye nokusebenza kakuhle.
ngelixa zombini i-carbomer kunye ne-hydroxyethylcellulose isebenza njenge-thickeners esebenzayo kunye ne-stabilizers kwi-formulation eyahlukeneyo, iyahluka ngokumalunga nokwakheka kweekhemikhali, i-molecular structure, i-solubility, i-thickening properties, i-compatibility, indawo yesicelo, iimpawu ze-sensory, kunye nokuqwalaselwa kokulawula. Ukuqonda lo mahluko kubalulekile ukuba abaqulunqi bakhethe esona sithako sifanelekileyo kwiimfuno zabo zemveliso ethile kunye neendlela zokusebenza.
Ixesha lokuposa: Apr-18-2024