I-Hydroxypropylmethylcellulose (HPMC) kunye ne-carboxymethylcellulose (CMC) ziindidi ezimbini ezahlukeneyo zeepolymers ezisetyenziselwa ukwakhiwa kwamehlo, zihlala zisetyenziselwa ukukhulula iimpawu zamehlo ezomileyo. Nangona babelana ngezinto ezifanayo, ezi zimbini zimbini zinomahluko ocacileyo kulwakhiwo lweekhemikhali, iipropathi, indlela yokusebenza, kunye nezicelo zeklinikhi.
IHydroxypropyl methylcellulose (HPMC) amathontsi emehlo:
1.Ulwakhiwo lwekhemikhali:
I-HPMC yimveliso eyenziweyo ye-cellulose, ipholima yendalo efumaneka kwiindonga zeeseli zesityalo.
Amaqela e-Hydroxypropyl kunye ne-methyl angeniswa kwisakhiwo se-cellulose, enika i-HPMC iipropati ezizodwa.
2. I-Viscosity kunye ne-rheology:
HPMC iliso amathontsi ngokubanzi viscosity eliphezulu ngaphezu kwamanye amathontsi zamehlo zokuthambisa ezininzi.
I-viscosity eyandisiweyo inceda amaconsi ukuba ahlale kwindawo ye-ocular ixesha elide, enika uncedo olude.
3. Indlela yokwenza:
I-HPMC yenza umaleko okhuselayo kunye nokuthambisa kwi-ocular surface, ukunciphisa ukukhuhlana kunye nokuphucula ukuzinza kwefilimu yeenyembezi.
Inceda ukuthomalalisa iimpawu zamehlo omileyo ngokunqanda ukuphuphuma okugqithisileyo kweenyembezi.
4. Isicelo soNyango:
I-HPMC eye drops idla ngokusetyenziswa ukunyanga isifo samehlo esomileyo.
Zikwasetyenziswa kuqhaqho lwamehlo kunye notyando ukugcina i-corneal hydration.
5. Izinto eziluncedo:
Ngenxa ye-viscosity ephezulu, inokwandisa ixesha lokuhlala kwindawo ye-ocular.
Ngokufanelekileyo ukhulula iimpawu zamehlo omileyo kwaye unika induduzo.
6. Izinto ezingeloncedo:
Abanye abantu banokuba nombono ophazamisayo ngokukhawuleza emva kokufakwa ngenxa yokwanda kwe-viscosity.
I-Carboxymethylcellulose (CMC) ithontsi yamehlo:
1.Ulwakhiwo lwekhemikhali:
I-CMC yenye i-cellulose derivative eguqulwe ngamaqela e-carboxymethyl.
Ukuqaliswa kweqela le-carboxymethyl kuphucula ukunyibilika kwamanzi, okwenza i-CMC ibe yipolymer enyibilikayo emanzini.
2. I-Viscosity kunye ne-rheology:
CMC iliso amathontsi ngokubanzi viscosity esezantsi xa kuthelekiswa HPMC amathontsi iliso.
I-viscosity esezantsi ivumela ukufakwa lula kunye nokusabalalisa ngokukhawuleza kwi-ocular surface.
3. Indlela yokwenza:
I-CMC isebenza njenge-lubricant kunye ne-humectant, iphucula uzinzo lwefilimu yeenyembezi.
Inceda ukukhulula iimpawu zamehlo omileyo ngokukhuthaza ukugcinwa komswakama kwindawo yamehlo.
4. Isicelo soNyango:
I-CMC eye drops isetyenziswa ngokubanzi ukukhulula iimpawu zamehlo omileyo.
Ziyacetyiswa ngokubanzi kubantu abane-syndrome yamehlo eyomileyo ephakathi ukuya kwephakathi.
5. Izinto eziluncedo:
Ngenxa ye-viscosity ephantsi, isasazeka ngokukhawuleza kwaye kulula ukuyikhupha.
Ngokufanelekileyo kwaye ngokukhawuleza ukhulula iimpawu zamehlo ezomileyo.
6. Izinto ezingeloncedo:
Idosi ethe kratya inokufunwa xa kuthelekiswa nokwakheka okuphezulu kwe-viscosity.
Amanye amalungiselelo anokuba nexesha elifutshane lesenzo kumphezulu we-ocular.
Uhlalutyo lothelekiso:
1. I-Viscosity:
I-HPMC ine-viscosity ephezulu, ibonelela ngesiqabu esihlala ixesha elide kunye nokhuseleko oluzinzileyo.
I-CMC ine-viscosity esezantsi, evumela ukusasazeka ngokukhawuleza kunye nokufaka lula.
2. Ubude bexesha:
I-HPMC ibonelela ngokubanzi ixesha elide lesenzo ngenxa ye-viscosity ephezulu.
I-CMC inokufuna ithamo elithe kratya, ngakumbi kwiimeko zeliso elomileyo kakhulu.
3. Ukuthuthuzela isigulana:
Abanye abantu banokufumanisa ukuba i-HPMC eyehlayo ekuqaleni ibangela ukufiphala okwethutyana kombono ngenxa ye-viscosity yabo ephezulu.
Amathontsi eliso e-CMC anyanyezelwa kakuhle kwaye abangela ukufiphala okuncinci kwasekuqaleni.
4. Iingcebiso zonyango:
I-HPMC icetyiswa ngokubanzi kubantu abane-syndrome yamehlo ephakathi ukuya kweyomileyo.
I-CMC iqhele ukusetyenziselwa amehlo athambileyo ukuya phakathi kwamehlo omileyo kunye nakwabo bakhetha ifomula ye-viscous encinci.
I-Hydroxypropylmethylcellulose (HPMC) kunye ne-carboxymethylcellulose (CMC) amathontsi eso zombini iindlela ezixabisekileyo zokunyanga iimpawu zamehlo omileyo. Ukhetho phakathi kwezi zibini luxhomekeke kukhetho lobuqu lwesigulana, ubukhali beliso elomileyo, kunye nexesha elifunekayo lesenzo. I-viscosity ephezulu ye-HPMC ibonelela ngokhuseleko oluhlala ixesha elide, ngelixa i-viscosity esezantsi ye-CMC ibonelela ngesiqabu esikhawulezayo kwaye inokuba lukhetho lokuqala kubantu abanovakalelo kumbono omfiliba. Iingcali zamehlo kunye nabasebenzi bokunakekelwa kwamehlo bahlala beqwalasela ezi zinto xa bekhetha amaconsi eehlo zokuthambisa ezifanelekileyo kwizigulana zabo, ezenzelwe ukukhulisa intuthuzelo kunye nokuphelisa ngokufanelekileyo iimpawu zamehlo omileyo.
Ixesha lokuposa: Dec-25-2023