Ukubonelela nge-ODM ngeHydroxypropyl Methyl Cellulose HPMC yoKwakha
Asiyi kuzama kuphela okusemandleni ethu ukubonisa iinkonzo ezincomekayo zengcaphephe kumthengi ngamnye, kodwa sikwakulungele ukufumana naziphi na iingcebiso ezibonelelwa ngamathuba ethu okubonelela nge-ODM Hydroxypropyl Methyl Cellulose HPMC yoKwakha, uphuculo olungasoze luphele kwaye sizabalazela ukusilela kwe-0% zezethu. Iipolisi ezimbini zomgangatho olungileyo. Ukuba ufuna nantoni na, ungalibazisi ukusitsalela umnxeba.
Asiyi kuzama kuphela ukunikezela ngeenkonzo ezincomekayo zengcaphephe kumthengi ngamnye, kodwa sikulungele ukufumana naziphi na iingcebiso ezibonelelwa ngamathuba ethu okuthenga.I-HPMC yaseTshayina kunye neBanga loKwakha, iimveliso zethu ezifanelekileyo zinegama elihle elivela kwihlabathi njengelona xabiso likhuphisanayo kunye nelona ncedo lwethu lwenkonzo emva kokuthengisa kubathengi. sinethemba lokuba sinokubonelela ngokukhuselekileyo, iimveliso zokusingqongileyo kunye nenkonzo ephezulu kubathengi bethu abavela kwihlabathi lonke kwaye ukuseka intsebenziswano yobuchule kunye nabo ngemigangatho yethu yobungcali kunye nemizamo engagungqiyo.
Ingcaciso yeMveliso
IHydroxypropyl Methyl Cellulose(HPMC)
Ifomula yeemolekyuli
IHypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokutshintsha 2910, 2906, 2208 (USP)
Iipropati Zomzimba
- Umgubo omhlophe okanye otyheli omhlophe
-Inyibilika kwisinyibilikisi esixutyiweyo okanye esinamanzi
- Ukwenza ifilimu ecacileyo xa ususa i-solvent
- Akukho ukuphendula kweekhemikhali kunye neziyobisi ngenxa yepropati yayo engeyiyo ionic
- Ubunzima beMolekyuli : 10,000 ~ 1,000,000
- Inqaku leGel: 40 ~ 90℃
Indawo yokutshisa ngokuzenzekelayo: 360℃
IHydroxypropyl Methylcellulose (HPMC) iBanga loShishino yi-Hypromellose excipient yeyeza kunye neyongezelelo, enokusetyenziswa njenge-thickener, dispersant, emulsifier kunye ne-agent-forming agent.
I-QualiCell Cellulose ether iqulethe i-methyl cellulose (USP, EP, BP, CP) kunye neentlobo ezintathu endaweni ye-hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) nganye ifumaneka kumabakala amaninzi ahlukeneyo kwimveliso ye-viscosity.HPMC ithathwe kwimveliso yendalo esulungekileyo i-cotton linter kunye ne-pulp yomthi, ukuhlangabezana nazo zonke iimfuno ze-USP, i-EP, i-BP, kunye ne-Kosher kunye Iziqinisekiso zeHalal.
Kwinkqubo yokuvelisa, ikotoni yendalo ehlanjululwe kakhulu i-etherified nge-methyl chloride okanye kunye nokudibanisa i-methyl chloride kunye ne-propylene oxide ukwenza i-ether e-soluble yamanzi, i-non-ionic cellulose ether. Akukho zixhobo zezilwanyana ezisetyenziselwa ukuveliswa kwe-HPMC.HPMC zingasetyenziswa njenge-binder kwiifom zedosi eqinileyo ezifana neepilisi kunye neegranules. Ikwasebenza nemisebenzi eyahlukeneyo, imizekelo, ekuphuculeni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid ekhuselayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, kunye nokubunjwa kwefilimu.
I-QualiCell HPMC inikezela ngemisebenzi eyahlukeneyo efana nokugcinwa kwamanzi, i-colloid yokukhusela, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Yikhompawundi engeyo-ionic exhathisayo kwityuwa ngaphandle kwaye izinzile kuluhlu olubanzi lwe-pH. Usetyenziso oluqhelekileyo lwe-HPMC zizibophelelo kwiifomu zedosi eqinileyo ezifana neepilisi kunye neegranuli okanye isingqimba sokwenziwa kolwelo.
I-Pharma HPMC iza kwiindidi ze-viscosity ezahlukeneyo ukusuka kwi-3 ukuya kwi-200,000 cps, kwaye ingasetyenziselwa ngokubanzi ukugquma ithebhulethi, i-granulation, i-binder, i-thickener, i-stabilizer kunye nokwenza i-capsule ye-HPMC yemifuno.
Ukucaciswa kwemichiza
| I-Hypromelose Inkcazo | 60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
IBanga leMveliso
| I-Hypromelose Inkcazo | 60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Isicelo
I-Pharma Grade HPMC yenza ukuba kuveliswe iifomyula ezilawulwayo-ezikhutshwayo ngokulula kweyona ndlela isetyenziswa kakhulu kwi-tablet-binding mechanism. IBanga le-Pharma libonelela ngokuhamba kakuhle komgubo, ukufana komxholo, kunye nokunyanzeliswa, kubenza bafanelekele ukunyanzeliswa ngokuthe ngqo.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| Unyibiliko lweLaxative | 75K4000,75K100000 | 3-30% |
| Iikhremu, iiGel | 60E4000,75K4000 | 1-5% |
| Ukulungiswa kwamehlo | 60E4000 | 01.-0.5% |
| Amalungiselelo amathontsi eliso | 60E4000 | 0.1-0.5% |
| I-arhente yokunqumamisa | 60E4000, 75K4000 | 1-2% |
| Ii-antacids | 60E4000, 75K4000 | 1-2% |
| Iitafile zeBinder | 60E5, 60E15 | 0.5-5% |
| Indibano eManzi iGranulation | 60E5, 60E15 | 2-6% |
| Iingubo zeCwecwe | 60E5, 60E15 | 0.5-5% |
| Ukukhutshwa okuLawulwayo kweMatrix | 75K100000,75K15000 | 20-55% |
Iimpawu kunye neeNzuzo
- Ukuphucula iimpawu zokuhamba kwemveliso
- Yehlisa amaxesha okusebenza
- Iiprofayili ezifanayo, ezizinzileyo zokupheliswa
- Ukuphucula ukufana komxholo
- Ukunciphisa iindleko zemveliso
- Igcina amandla okuqina emva kokudityaniswa kabini (i-roller compaction) inkqubo
Ukupakishwa
Ukupakishwa okusemgangathweni yi-25kg / igubu
I-20'FCL: iitoni ezili-9 ezine-palletized; Iitoni ezili-10 ezingafakwanga iipaleti.
I-40'FCL: i-18 toni ene-palletized; I-20 ton unpalletized.Asiyi kuzama kuphela ukunikezela ngeenkonzo zengcaphephe ezincomekayo kumthengi ngamnye, kodwa sikulungele ukufumana naziphi na iingcebiso ezinikezelwa ngamathemba ethu obonelelo nge-ODM Hydroxypropyl Methyl Cellulose HPMC yoKwakha, Uphuculo olungasoze luphele kwaye sizame 0 % intsilelo yimigaqo-nkqubo yethu emibini yomgangatho olungileyo. Ukuba ufuna nantoni na, ungalibazisi ukusitsalela umnxeba.
Ukubonelela nge-ODMI-HPMC yaseTshayina kunye neBanga loKwakha, iimveliso zethu ezifanelekileyo zinegama elihle elivela kwihlabathi njengelona xabiso likhuphisanayo kunye nelona ncedo lwethu lwenkonzo emva kokuthengisa kubathengi. sinethemba lokuba sinokubonelela ngokukhuselekileyo, iimveliso zokusingqongileyo kunye nenkonzo ephezulu kubathengi bethu abavela kwihlabathi lonke kwaye ukuseka intsebenziswano yobuchule kunye nabo ngemigangatho yethu yobungcali kunye nemizamo engagungqiyo.
