Ngaba unokungadibani ne-HPMC?

I-Hypromellose, eyaziwa njenge-HPMC (i-hydroxypropyl methylcellulose), yikhompawundi esetyenziswa ngokubanzi kumashishini ahlukeneyo, kubandakanywa amayeza, ukutya, kunye nezithambiso.Isebenza ngeenjongo ezininzi, ezifana ne-agent ejiyayo, i-emulsifier, kunye nenye indlela yokutya imifuno kwi-gelatin kumaqokobhe e-capsule.Nangona kunjalo, ngaphandle kokusetyenziswa kwayo ngokubanzi, abanye abantu banokufumana ukusabela okungathandekiyo kwi-HPMC, ebonakala njengeempendulo ezichaseneyo.

1. Ukuqonda i-HPMC:

I-HPMC yi-polymer ye-semisynthetic ephuma kwi-cellulose kwaye iguqulwe ngeenkqubo zemichiza.Inezinto ezininzi ezinqwenelekayo, kubandakanya ukunyibilika kwamanzi, ukuhambelana kwebhayoloji, kunye nokungabi natyhefu, kuyenza ilungele usetyenziso olwahlukeneyo.Kumachiza, i-HPMC isetyenziswa rhoqo kwiipilisi zeepilisi, iifomyula ezilawulwayo, kunye nezisombululo ze-ophthalmic.Ukongeza, isebenza njenge-stabilizer kunye ne-ejenti yokuqina kwiimveliso zokutya, ezinje ngeesosi, isuphu, kunye ne-ayisikhrim, ngelixa ikwafumana into eluncedo kwiindlela zokuthambisa ezifana neekhrimu kunye neloshini.

2.Ungakwazi Ukwalana ne-HPMC?

Ngelixa i-HPMC ithathwa njengekhuselekile ngokubanzi ukuba ingasetyenziswa kunye nesicelo se-topical, ukuchasana nokwaliwa kule khompawundi kuye kwaxelwa, nangona kunqabile.Iimpendulo ze-aleji zenzeka xa amajoni omzimba achonga ngempazamo i-HPMC njengeyingozi, ibangela ukudumba kwe-cascade.Ezona nkqubo ziseza kukwaliwa yi-HPMC zihlala zingacacanga, kodwa uqikelelo lucebisa ukuba abantu abathile banokuba ne-immune predisposition okanye uvakalelo kumalungu athile ekhemikhali ngaphakathi kwe-HPMC.

3.IiMpawu ze-HPMC zokwalana:

Iimpawu ze-HPMC zokwaliwa zinokwahluka ngokobuqatha kwaye zinokubonakala kwakamsinyane emva kokuba sesichengeni okanye ngokulibaziseka.Iimpawu eziqhelekileyo ziquka:

Iintshukumo zolusu: Oku kunokubandakanya ukurhawuzelelwa, ukubabomvu, ukurhawuzelela (urticaria), okanye irhashalala efana ne-eczema xa udibana neemveliso ezine-HPMC.

Iimpawu zokuphefumla: Abanye abantu banokufumana ubunzima bokuphefumla, njengokuphefumla, ukukhohlela, okanye ukuphefumla kancinci, ngakumbi xa uphefumla amasuntswana omoya ane-HPMC.

Uxinzelelo lweGastrointestinal: Iimpawu zokwetyisa ezifana nesicaphucaphu, ukuhlanza, iintlungu zesisu, okanye urhudo lunokwenzeka emva kokusela amayeza aqulathe i-HPMC okanye izinto zokutya.

I-Anaphylaxis: Kwiimeko ezinzima, i-HPMC yokwaliwa ingakhokelela kwi-anaphylactic shock, ebonakala ngokuhla ngokukhawuleza koxinzelelo lwegazi, ukuphefumla nzima, ukubetha ngokukhawuleza, kunye nokulahlekelwa zingqondo.I-Anaphylaxis ifuna unyango olukhawulezileyo njengoko inokubeka ubomi esichengeni.

4. Uxilongo lwe-HPMC Yokwalana:

Ukuxilongwa kwe-HPMC yokwaliwa kusenokuba ngumngeni ngenxa yokunqongophala kweemvavanyo ezisemgangathweni zokwaliwa ezithe ngqo kule khompawundi.Nangona kunjalo, abaqeqeshi bezempilo banokusebenzisa ezi ndlela zilandelayo:

Imbali yezoNyango: Imbali ecacileyo yeempawu zesigulane, kubandakanywa ukuqala kwabo, ubude bexesha, kunye nokudibanisa nokuvezwa kwe-HPMC, kunokubonelela ngeengcamango ezibalulekileyo.

Uvavanyo lwePatch yolusu: Uvavanyo lwePatch lubandakanya ukusebenzisa iimali ezincinci zezisombululo ze-HPMC eluswini phantsi kwe-occlusion ukujonga ukusabela okwaliwayo ngexesha elithile.

Uvavanyo lwe-Provocation: Kwezinye iimeko, i-allergists inokwenza iimvavanyo ze-oral or inhalation provocation phantsi kweemeko ezilawulwayo ukuvavanya impendulo yesigulane kwi-HPMC exposure.

Ukuphelisa Ukutya: Ukuba i-HPMC i-allergies ikrokrelwa ngenxa yokungeniswa ngomlomo, ukutya okuphelisa kunokucetyiswa ukuba kuchongwe kwaye kususwe ukutya okune-HPMC ekutyeni komntu kunye nokubeka iliso ekusonjululweni kweempawu.

5.Ulawulo lwe-HPMC Yokwalana:

Nje ukuba ufunyaniswe, ukulawula ukwaliwa kwe-HPMC kubandakanya ukunqanda ukuba sesichengeni kwiimveliso eziqulathe le khompawundi.Oku kusenokufuna uqwalaselo ngononophelo lweelebhile zezithako kumayeza, ukutya, kunye nezithambiso.Iimveliso ezizezinye ezisimahla kwi-HPMC okanye ezinye iikhompawundi ezinxulumene nazo zinokucetyiswa.Kwiimeko zokuvezwa ngengozi okanye ukuchasana kakhulu, abantu kufuneka baphathe amayeza kaxakeka afana ne-epinephrine auto-injection kwaye bafune unyango olukhawulezileyo.

Nangona kunqabile, ukuchasana ne-HPMC kunokuthi kwenzeke kwaye kubangele imingeni ebalulekileyo kubantu abachaphazelekayo.Ukuqaphela iimpawu, ukufumana uxilongo oluchanekileyo, kunye nokuphumeza izicwangciso ezifanelekileyo zokulawula kubalulekile ekudambiseni imingcipheko eyayanyaniswa nokwaliwa yi-HPMC.Uphando olongezelelweyo luyafuneka ukuze kuqondwe ngcono iindlela ze-HPMC zokwazisa nokuphuhlisa iimvavanyo zokuxilonga ezisemgangathweni kunye nongenelelo lonyango kubantu abachaphazelekayo.Okwangoku, abaqeqeshi bezempilo kufuneka bahlale bephaphile kwaye besabela kwizigulana ezibonisa ukurhaneleka kwe-HPMC yokwaliwa, ukuqinisekisa uphononongo olungexesha kunye nokhathalelo olubanzi.