IHydroxypropylmethylcellulose (HPMC) yipolymer eyenziwe ngokuguqula i-cellulose yendalo.Ineentlobo ngeentlobo zezicelo zemizi-mveliso kumayeza, ukutya, izinto zokuthambisa, kunye nokwakha.I-HPMC yi-ether ye-cellulose ye-nonionic enyibilika ngokulula emanzini kwaye inokwenza isisombululo esicacileyo, esine-viscous esihlala sizinzile kuluhlu olubanzi lwe-pH.
Iimpawu zeHPMC ziquka:
1. Umthamo ophezulu wokugcinwa kwamanzi: I-HPMC inokufunxa amanzi kwaye iwabambe endaweni, iyenze ibe luncedo njenge-thickener, emulsifier, kunye ne-stabilizer kwizicelo ezininzi.
2. Iipropati ezilungileyo zokwenza ifilimu: I-HPMC inokwenza iifilimu ezicacileyo kunye namandla afanelekileyo omatshini.Oku kuvumela ukuba kusetyenziswe ukuveliswa kwee-capsules, iingubo kunye nezinye iimveliso.
3. Umsebenzi ophezulu womphezulu: I-HPMC ineempawu ezisebenzayo, ezivumela ukuba zisetyenziswe njenge-agent yokumanzisa kunye ne-dispersant.
4. Ukuzinza okuhle kwe-thermal: I-HPMC izinzile kumaqondo aphezulu kwaye ingasetyenziselwa izicelo ezifuna le ntsebenzo.
5. Ukubambelela kakuhle kwiindawo ezahlukeneyo: I-HPMC inokudibanisa kwiindawo ezininzi, okwenza kube luncedo ekuveliseni izinto zokuncamathelisa kunye neengubo.
Ukusetyenziswa kweHPMC kumashishini ahlukeneyo:
1. Iyeza: I-HPMC isetyenziswa ngokubanzi kumalungiselelo amayeza njenge-binder, i-disintegrant, kunye ne-viscosity regulator.Ifumaneka kwiipilisi, ii-capsules kunye ne-liquid formulations.
2. Ukutya: I-HPMC isetyenziswa njenge-thickener, stabilizer kunye ne-emulsifier ekutyeni.Ingasetyenziswa kwiimveliso ezifana ne-ayisikrimu, iyogathi kunye nokunxitywa kwesaladi.
3. Izithambiso: I-HPMC isetyenziswa kakhulu kwizinto zokuthambisa njenge-thickener, emulsifier, kunye ne-agent-forming agent.Ingasetyenziswa kwiimveliso ezifana ne-creams, lotions kunye neshampu.
4. Ulwakhiwo: I-HPMC sisithako esiphambili kwizinto ezininzi zokwakha ezifana nokunamathiswa kweethayile, iiplaster ezenziwe ngesamente kunye nodaka.Isebenza njenge-ejenti yokugcina amanzi, iphucula ukusebenza, kwaye ibonelela ngokubambelela okungcono kunye nokulawulwa kokunciphisa.
Umlinganiselo wesalathiso kwishishini le-HPMC:
1. Ukugcinwa kwamanzi: Izinga lokugcinwa kwamanzi kwe-HPMC yiparameter ebalulekileyo emisela ukusebenza kwayo njenge-thickener kunye ne-adhesive.Ipropati inereyithi yereferensi yoshishino ye-80-100%.
2. I-Viscosity: I-Viscosity yiparameter ephambili ekukhetheni i-HPMC kwizicelo ezahlukeneyo.Ireyishini yereferensi yeshishini le-viscosity isukela kwi-5,000 ukuya kwi-150,000 mPa.s.
3. Umxholo weqela le-Methoxyl: Umxholo weqela le-methoxyl le-HPMC lichaphazela ukunyibilika kwayo, i-viscosity kunye ne-bioavailability.Umlinganiselo wereferensi yeshishini lomxholo we-methoxy uphakathi kwe-19% kunye ne-30%.
4. Umxholo we-Hydroxypropyl: Umxholo we-hydroxypropyl uchaphazela ukunyibilika kunye ne-viscosity ye-HPMC.Umlinganiselo wereferensi yeshishini lomxholo we-hydroxypropyl uphakathi kwe-4% kunye ne-12%.
I-HPMC yipolymer eguquguqukayo enezicelo ezininzi zemizi-mveliso.Iimpawu zayo ezikhethekileyo zenza ukuba zilungele ukusetyenziswa kumachiza, ukutya, izimonyo kunye nokwakhiwa.Ireyishini yereferensi yoshishino yeeparamitha ezahlukeneyo inceda ekukhetheni ibakala elifanelekileyo le-HPMC kwisicelo esithile.
Ixesha lokuposa: Sep-14-2023