Ukunyibilika kwe-HPMC

IHydroxypropyl methylcellulose (HPMC) iyanyibilika emanzini, enye yezona zinto zibalulekileyo kwaye inegalelo ekusetyenzisweni kwayo ngeendlela ezahlukahlukeneyo.Xa ifakwe emanzini, i-HPMC isasaza kwaye i-hydrates, isenza izisombululo ezicacileyo kunye ne-viscous.Ukunyibilika kwe-HPMC kuxhomekeke kwizinto ezininzi, kubandakanywa iqondo lokutshintshela (DS), ubunzima bemolekyuli yepolymer, kunye nobushushu besisombululo.

Ngokubanzi, i-HPMC enamaxabiso asezantsi e-DS ithande ukunyibilika ngakumbi emanzini xa kuthelekiswa ne-HPMC enamaxabiso aphezulu e-DS.Ngokufanayo, i-HPMC enamabanga asezantsi obunzima bemolekyuli inokuba namazinga okupheliswa okukhawulezayo xa kuthelekiswa namabakala aphezulu obunzima bemolekyuli.

Ubushushu besisombululo bukwachaphazela ukunyibilika kwe-HPMC.Amaqondo obushushu aphezulu aphucula ukunyibilika kwe-HPMC, evumela ukunyibilika ngokukhawuleza kunye nokuhanjiswa kwamanzi.Nangona kunjalo, izisombululo ze-HPMC zinokungena kwi-gelation okanye ukwahlukana kwesigaba kumaqondo obushushu aphakamileyo, ngakumbi kwiindawo eziphezulu.

Kubalulekile ukuqaphela ukuba ngelixa i-HPMC inyibilika emanzini, izinga kunye nobungakanani bokuchithwa bunokwahluka ngokuxhomekeke kwibakala elithile le-HPMC, iimeko zokwenziwa, kunye nazo naziphi na ezinye izongezo ezikhoyo kwinkqubo.Ukongeza, i-HPMC inokubonisa iimpawu ezahlukeneyo zokunyibilika kwizinyibilikisi eziphilayo okanye ezinye iinkqubo ezingenamanzi.

ukunyibilika kwe-HPMC emanzini kuyenza ibe yipolymer exabisekileyo kwizicelo ezahlukeneyo apho ukuguqulwa kwe-viscosity, ukwenziwa kwefilimu, okanye ezinye izinto ezifunekayo.