Ukugcinwa kwamanzi kuyipropati ebalulekileyo kumashishini amaninzi asebenzisa izinto ze-hydrophilic ezifana ne-cellulose ethers.IHydroxypropylmethylcellulose (HPMC) yenye ye-cellulose ethers eneempawu eziphezulu zokugcina amanzi.I-HPMC yi-semi-synthetic polymer ephuma kwi-cellulose kwaye iqhele ukusetyenziswa kwiintlobo ngeentlobo zezicelo kumashishini okwakha, amayeza kunye nokutya.
I-HPMC isetyenziswa ngokubanzi njengento etyebisayo, isizinzisi kunye ne-emulsifier kwiimveliso zokutya ezahlukeneyo ezifana ne-ayisikrimu, iisosi kunye nokunxitywa ukunyusa ukuthungwa kwazo, ukungaguquguquki kunye nobomi beshelufu.I-HPMC ikwasetyenziswa ekuveliseni amayeza kwishishini loxubo-mayeza njengesibophelelo, i-disintegrant kunye ne-agent yokugquma ifilimu.Ikwasetyenziswa njengearhente yokugcina amanzi kwizinto zokwakha, ikakhulu kwisamente kunye nodaka.
Ukugcinwa kwamanzi yipropathi ebalulekileyo ekwakhiweni kuba inceda ukugcina isamente esandula ukuxutywa nodaka ukuba lome.Ukomisa kunokubangela ukuncipha kunye nokuqhekeka, okukhokelela kwizakhiwo ezibuthathaka nezingazinzanga.I-HPMC inceda ukugcina isiqulatho samanzi kwisamente kunye nodaka ngokufunxa iimolekyuli zamanzi kwaye ngokucothayo uwakhulule ngokuhamba kwexesha, evumela izinto zokwakha ukuba zinyange ngokufanelekileyo kwaye ziqine.
Umgaqo wokugcinwa kwamanzi we-HPMC usekwe kwi-hydrophilicity yayo.Ngenxa yobukho bamaqela e-hydroxyl (-OH) kwisakhiwo sayo se-molecular, i-HPMC inobudlelwane obuphezulu bamanzi.Amaqela e-hydroxyl asebenzisana neemolekyuli zamanzi ukwenza iibhondi ze-hydrogen, ezikhokelela ekwenziweni kweqokobhe le-hydration elijikeleze i-polymer chain.Iqokobhe le-hydrated livumela amakhonkco e-polymer ukuba andise, ukwandisa umthamo we-HPMC.
Ukudumba kwe-HPMC yinkqubo eguquguqukayo exhomekeke kwizinto ezahlukeneyo ezifana ne-degree of substitution (DS), ubungakanani bamasuntswana, ubushushu kunye ne-pH.Iqondo lokutshintsha libhekisa kwinani lamaqela e-hydroxyl afakwe endaweni yeyunithi nganye ye-anhydroglucose kwikhonkco leselulosi.Iphezulu ixabiso le-DS, iphezulu i-hydrophilicity kwaye ngcono ukusebenza kokugcinwa kwamanzi.Ubungakanani bamasuntswana e-HPMC bukwachaphazela ukugcinwa kwamanzi, njengoko amasuntswana amancinci anommandla omkhulu womphezulu weyunithi nganye, okukhokelela ekufunxeni okukhulu kwamanzi.Ubushushu kunye nexabiso le-pH lichaphazela iqondo lokudumba nokugcinwa kwamanzi, kunye nobushushu obuphezulu kunye nexabiso eliphantsi le-pH liphucula ukudumba nokugcinwa kwamanzi kwiipropati zeHPMC.
Indlela yogcino lwamanzi ye-HPMC ibandakanya iinkqubo ezimbini: ukufunxa kunye nokukhutshwa.Ngexesha lokufunxa, i-HPMC ifunxa iimolekyuli zamanzi kwindawo engqongileyo, yenze iqokobhe le-hydration elijikeleze amatyathanga epolymer.Iqokobhe le-hydration lithintela amatyathanga epolymer ukuba angawi kwaye awagcine ahlukene, okukhokelela ekudumbeni kweHPMC.Iimolekyuli zamanzi ezifunxayo zenza iibhondi ze-hydrogen kunye namaqela e-hydroxyl kwi-HPMC, ephucula ukusebenza kokugcinwa kwamanzi.
Ngexesha le-desorption, i-HPMC ikhupha kancinci iimolekyuli zamanzi, ivumela ukuba izinto zokwakha zinyange ngokufanelekileyo.Ukukhutshwa okucothayo kwama-athomu amanzi kuqinisekisa ukuba i-samente kunye nodaka luhlala lugcwele i-hydrated ngokupheleleyo, okubangelwa isakhiwo esizinzileyo kunye nesigxina.Ukukhutshwa okucothayo kweeamolekyu zamanzi kwakhona kunika ukunikezelwa kwamanzi rhoqo kwi-samente kunye nodaka, ukunyusa inkqubo yokunyanga kunye nokwandisa amandla kunye nokuzinza kwemveliso yokugqibela.
Isishwankathelo, ukugcinwa kwamanzi kuyipropati ebalulekileyo kumashishini amaninzi asebenzisa izinto ze-hydrophilic ezifana ne-cellulose ethers.I-HPMC yenye yee-ether ze-cellulose ezineempawu eziphezulu zokugcina amanzi kwaye isetyenziswa ngokubanzi kumashishini okwakha, amayeza kunye nokutya.Iimpawu zokugcina amanzi ze-HPMC zisekwe kwi-hydrophilicity yayo, eyenza ukuba ikwazi ukufunxa iimolekyuli zamanzi kwindawo engqongileyo, zenze iqokobhe le-hydration elijikeleze amakhonkco e-polymer.Igobolondo le-hydrated libangela ukuba i-HPMC idumbe, kwaye ukukhutshwa okucothayo kweeamolekyu zamanzi kuqinisekisa ukuba izinto zokwakha zihlala zigcwele i-hydrated ngokupheleleyo, okubangelwa isakhiwo esizinzileyo kunye nesigxina.
Ixesha lokuposa: Aug-24-2023